Área de PDI em Farmacologia, Fisiopatologia, Inovações Terapêuticas e Bioprodutos 2008
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Accioly MT, Pacheco P, Maya-Monteiro CM, Carrossini N, Robbs BK, Oliveira SS, Kaufmann C, Morgado-Diaz JA, Bozza PT, Viola JP. 2008. Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells. Cancer Res. 5;68(6):1732-40.
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Aimbire F, Santos FV, Albertini R, Castro-Faria-Neto HC, Mittmann J, Pacheco-Soares C. 2008. Low-level laser therapy decreases levels of lung neutrophils anti-apoptotic factors by a NF-kappaB dependent mechanism. Int Immunopharmacol. 8(4):603-5.
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Andrade HM, Murta SM, Chapeaurouge A, Perales J, Nirdé P, Romanha AJ. 2008. Proteomic analysis of Trypanosoma cruzi resistance to benznidazole. J Proteome Res. 7(6):2357-67.
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Baldo C, Tanjoni I, León IR, Batista IF, Della-Casa MS, Clissa PB, Weinlich R, Lopes-Ferreira M, Lebrun I, Amarante-Mendes GP, Rodrigues VM, Perales J, Valente RH, Moura-da-Silva AM. 2008. BnP1, a novel P-I metalloproteinase from Bothrops neuwiedi venom: Biological effects benchmarking relatively to jararhagin, a P-III SVMP. Toxicon Volume 51, Issue 1, Pages 54-65
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Cabral MM, Crescente ER, Mendonça PM, Gomes CM, Oliveira VC, Kelecom A. 2008. Melia azedarach L. extracts and their activity on Musca domestica L. (Diptera: Muscidae). Revista Brasileira de Farmacognosia. Vol. 18 (Suppl): 669-702.
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Cabral MM, Garcia ES, Gottlieb OR, Kelecom A. 2008. Degradation of the neolignan, burchellin in the hemolymph of the bloodsucking insect Rhodnius prolixus. FitoterapiaVolume 79, Issue 1, 59-63.
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Cavalher-Machado SC, Cuman RK, Sartoretto JL, Martins JO, de Lima WT, Martins MA, Silva PM, Sannomiya P. 2008. The allergic inflammatory reaction in neonatal streptozotocin-induced diabetic rats: evidence of insulin resistance and microvascular dysfunction. Inflamm Res. 2008 Nov;57(11):535-41.
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Carvalho PC, Junqueira M, Valente RH and Domont GB. 2008. Caititu: a tool to graphically represent peptide sequence coverage and domain distribution. Journal of ProteomicsVolume 71, Issue 4, 7 October 2008, Pages 486-489
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Carvalho S, Cortez E, Stumbo AC, Thole A, Caetano C, Marques R, Pelajo-Machado M, Porto LC, Carvalho L. 2008. Laminin expression during bone marrow mononuclear cell transplantation in hepatectomized rats. Cell Biology International. Volume 32, Issue 8, 1014-1018.
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Carvalho VF, Campos LV, Farias-Filho FA, Florim LT, Barreto EO, Pirmez C, Savino W, Martins MA, Silva PMR. Suppression of allergic inflammatory response in the skin of alloxan-diabetic rats: Relationship with reduced local mast cell numbers. Int Arch Allergy Immunol 2008;147:246-254
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Costa HF, Bezerra-Santos CR, Barbosa Filho JM, Martins MA, Piuvezam MR. 2008. Warifteine, a bisbenzylisoquinoline alkaloid, decreases immediate allergic and thermal hyperalgesic reactions in sensitized animals. International Immunopharmacology. Volume 8, Issue 4, April 2008, Pages 519-525.
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Cirne-Santos CC, Souza TML, Teixeira VL, Fontes CFL, Rebello MA, Castello-Branco LRR, Abreu CM, Tanuri A, Frugulhetti ICPP, Bou-Habib DC. The dolabellane diterpene Dolabelladienetriol is a typical noncompetitive inhibitor of HIV-1 reverse transcriptase enzyme. Antiviral Research, Volume 77, Issue 1, January 2008, Pages 64-71.
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Coelho LP, Serra MF, Pires AL, Cordeiro RS, Rodrigues e Silva PM, dos Santos MH, Martins MA. 2008. 7-Epiclusianone, a tetraprenylated benzophenone, relaxes airway smooth muscle through activation of the nitric oxide-cGMP pathway. JPET 327:206-214.
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Costa JC, Neves JS, de Souza MV, Siqueira RA, Romeiro NC, Boechat N, e Silva PM, Martins MA. 2008. Synthesis and antispasmodic activity of lidocaine derivatives endowed with reduced local anesthetic action. Bioorg Med Chem Lett. 18(3):1162-6.
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D'Avila H, Maya-Monteiro CM, Bozza PT. 2008. Lipid bodies in innate immune response to bacterial and parasite infections. Int Immunopharmacol. 8(10):1308-15.
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D'Avila H, Roque NR, Cardoso RM, Castro-Faria-Neto HC, Melo RC, Bozza PT. 2008. Neutrophils recruited to the site of Mycobacterium bovis BCG infection undergo apoptosis and modulate lipid body biogenesis and Prostaglandin E2. Cellular Microbiology. V 10 Issue 12, P 2589 – 2604.
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de Moraes R, Valente RH, León IR, Trugilho MR, Nóbrega AC, Perales J, Tibiriçá E. 2008. Chronic dynamic exercise increases apolipoprotein A-I expression in rabbit renal cortex as determined by proteomic technology. Br J Sports Med. 42(5):386-8.
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de Paiva LS, Nobrega A, De Melo GO, Hayashi EA, Carvalho V, Rodrigues E Silva PM, Bellio M, Teixeira GP, Rumjanek V, Costa SS, Koatz VL.. 2008.Selective blockade of lymphopoiesis induced by kalanchosine dimalate: inhibition of IL-7-dependent proliferation. J Leukoc Biol. 2008 Apr;83(4):1038-48.
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Fischer JS, Carvalho PC, Neves-Ferreira AG, da Fonseca CO, Perales J, Carvalho Mda G, Domont GB. 2008. Anti-thrombin as a prognostic biomarker candidate for patients with recurrent glioblastoma multiform under treatment with perillyl alcohol. J Exp Ther Oncol. Vol. 7(4):285-90.
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Freitas FZ, Chapeaurouge A, Perales J, Bertolini MC. 2008. A systematic approach to identify STRE-binding proteins of the gsn glycogen synthase gene promoter in Neurospora crassa. Proteomics. Volume 8 Issue 10, Pages 2052 – 2061.
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Gomes MB, Matheus AS, Tibiriçá E. 2008. Evaluation of microvascular endothelial function in patients with type 1 diabetes using laser-Doppler perfusion monitoring: which method to choose? Microvasc Res. 76(2):132-3.
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Gomes MD, Cobas RA, Nunes E, Nery M, Castro-Faria-Neto HC, Tibiriçá E. 2008. Serum platelet-activating factor acetylhydrolase activity: A novel potential inflammatory marker in type 1 diabetes. Prostaglandins Other Lipid Mediat. 87 (1-4): 42-46
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Guedes HL, Silva FP Jr, Netto CC, de Salles CM, Alexandre G, Oliveira CL, Torriani I, De Simone SG. 2008. Structural characterization and low-resolution model of BJ-48, a thrombin-like enzyme from Bothrops jararacussu venom. Biophys Chem. 132 (2-3):159-64.
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Jannotti-Passos LK, Andrade HM, Caldeira RL, Romanha AJ, Murta SM, Chapeaurouge DA, Perales J, Coelho PM, Carvalho OS. 2008. Proteome analysis of the cardiac and pericardial tissue of Biomphalaria tenagophila populations susceptible and resistant to Schistosoma mansoni infection. Acta Tropica Volume 105, Issue 3, March 2008, Pages 229-234.
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Korenblum, E., Sebastián, G., Paiva, M.M., Coutinho, C., Magalhães, F., Peyton, B., Seldin, L. 2008. Action of antimicrobial substances produced by different oil reservoir Bacillus strains against biofilm formation. Applied Microbiology and Biotechnology, Volume 79, Number 1, pp. 97-103(7).
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Leite-Junior JH, Garcia CS, Souza-Fernandes AB, Silva PL, Ornellas DS, Larangeira AP, Castro-Faria-Neto HC, Morales MM, Negri EM, Capelozzi VL, Zin WA, Pelosi P, Bozza PT, Rocco PR. 2008. Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice. Crit Care Med. 36(9):2621-8.
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Lery LM, Coelho A, von Kruger WM, Gonçalves MS, Santos MF, Valente RH, Santos EO, Rocha SL, Perales J, Domont GB, Teixeira KR, Bertalan M, Ferreira PC, Bisch PM.. 2008. Protein expression profile of Gluconacetobacter diazotrophicus PAL5, a sugarcane endophytic plant-growth promoting bacterium. PROTEOMICS - Clinical Applications. V 8 Issue 8, Pages 1631 – 1644.
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Lessa MA, Araújo CV, Kaplan MA, Pimenta D, Figueiredo MR, Tibiriçá E. 2008. Antihypertensive effects of crude extracts from leaves of Echinodorus grandiflorus. Fundamental & Clinical Pharmacology, Volume 22, Number 2, April 2008 , pp. 161-168
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Maya-Monteiro CM ; Bozza, P T . 2008. Leptin and mTOR: partners in metabolism and inflammation. Cell Cycle, v. 7, p. 1713-1717, 2008.
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Maya-Monteiro CM; Almeida, P. E. ; Davila, H.; Martins, A. S.; Rezende, A. P.; Castro- Faria- Neto, H.C.; Bozza, P. T. 2008. Leptin induces macrophage lipid body formation by a phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent mechanism. Journal of Biological Chemistry (Online), v. 25, p. 2203-2210.
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Miyazaki Y, Bunting M, Stafforini DM, Harris ES, McIntyre TM, Prescott SM, Frutuoso VS, Amendoeira FC, de Oliveira Nascimento D, Vieira-de-Abreu A, Weyrich AS, Castro-Faria-Neto HC, Zimmerman GA. 2008. Integrin alphaDbeta2 is dynamically expressed by inflamed macrophages and alters the natural history of lethal systemic infections. J Immunol. 180(1):590-600.
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Neves JS, Perez SA, Spencer LA, Melo RC, Reynolds L, Ghiran I, Mahmudi-Azer S, Odemuyiwa SO, Dvorak AM, Moqbel R, Weller PF. 2008. Eosinophil granules function extracellularly as receptor-mediated secretory organelles. Proc Natl Acad Sci U S A. Vol. 105(47):18478-83.
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Oliveira MS, de O Barreto E, Zamuner S, Pires AL, Ferreira TP, Cordeiro RS, Lagente V, Martins MA, Wallace JL, E Silva PM. 2008. Suppressive effects of nitric oxide-releasing prednisolone NCX-1015 on the allergic pleural eosinophil recruitment in rats. Clinical & Experimental Allergy. Vol.38 (11): 1830 – 1837.
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Plotkowski MC, Brandão BA,de Assis MC,Feliciano LF,Raymond B,Freitas C,Saliba AM,Zahm JM,Touqui L,Bozza PT. 2008. Lipid body mobilization in the ExoU-induced release of inflammatory mediators by airway epithelial cells. Microbial pathogenesis. V 45 Ed: 1 Pág: 30-7.
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Possuelo LG, Castelan JA, de Brito TC, Ribeiro AW, Cafrune PI, Picon PD, Santos AR, Teixeira RL, Gregianini TS, Hutz MH, Rossetti ML, Zaha A. 2008. Association of slow N-acetyltransferase 2 profile and anti-TB drug-induced hepatotoxicity in patients from Southern Brazil. Eur J Clin Pharmacol. Jul;64(7):673-81. Sabino, B.; Lessa, M. A. ; Nascimento, A. R. ; Rodrigues, C. A. B. ; Henriques, M. G. ; Garzoni, L. R. ; Levy Bi ; Tibiriçá, E. 2008. Effects of antihypertensive drugs on capillary rarefaction in spontaneously hypertensive rats: intravital microscopy and histological analysis. Journal of Cardiovascular Pharmacology, v. 51, p. 402-409.
Sabino, B.; Lessa, M. A. ; Nascimento, A. R. ; Rodrigues, C. A. B. ; Henriques, M. G. ; Garzoni, L. R. ; Levy Bi ; Tibiriçá, E. 2008. Effects of antihypertensive drugs on capillary rarefaction in spontaneously hypertensive rats: intravital microscopy and histological analysis. Journal of Cardiovascular Pharmacology, v. 51, p. 402-409.
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Salluh JI, Bozza FA, Soares M, Verdeal JC, Castro-Faria-Neto HC, Lapa E Silva JR, Bozza PT.. 2008. Adrenal response in severe community-acquired pneumonia: Impact on outcomes and disease severity. Chest.
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Salluh JI, Bozza PT. 2008. Biomarkers of sepsis: Lost in translation? Crit Care Med. Jul;36(7):2014-22.
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Salluh JI, Bozza PT, Bozza FA. 2008. Surviving sepsis campaign: A critical reappraisal. Shock. Suppl 1:70-2.
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Salluh JI, Póvoa P, Soares M, Castro-Faria-Neto HC, Bozza FA, Bozza PT. 2008. The role of corticosteroids in severe community-acquired pneumonia: a systematic review. Crit Care. 2008; 12(3): R76.
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Salluh JI, Soares M. New recommendations for the use of corticosteroids in sepsis: not so fast!Crit Care Med. 2008 Aug;36(8):2489-90; author reply 2490.
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Salomão K, Pereira PRS, Campos LC, Borba CM, Cabello PH, Marcucci MC e de Castro SL. 2008. Brazilian Propolis: Correlation Between Chemical Composition and Antimicrobial Activity. Evidence Based Complementart and Alternative Medecine. 5(3): 317–324.
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Silva- FP Jr, Alexandre GM, Ramos CH, De-Simone SG. 2008. On the quaternary structure of a C-type lectin from Bothrops jararacussu venom-BJ-32 (BjcuL). Toxicon.
