Área de PDI em Doença de Chagas 2012
Almeida CE, Oliveira HL, Correia N, Dornak LL, Gumiel M, Neiva VL, Harry M, Mendonça VJ, Costa J, Galvão C. Dispersion capacity of Triatoma sherlocki, Triatoma juazeirensis and laboratory-bred hybrids. Acta Trop. 2012 Apr;122(1):71-9. http://www.sciencedirect.com/science/article/pii/S0001706X11003469
Araújo-Jorge TC, Waghabi MC, Bailly S, Feige JJ. The TGF-β pathway as an emerging target for Chagas disease therapy. Clin Pharmacol Ther. 2012 Nov;92(5):613-21. Epub 2012 Sep 19. http://www.ncbi.nlm.nih.gov/pubmed/22990752
Calvet CM, Melo TG, Garzoni LR, Oliveira FO Jr, Neto DT, N S L M, Meirelles L, Pereira MC. Current understanding of the Trypanosoma cruzi-cardiomyocyte interaction. Front Immunol. 2012;3:327. Epub 2012 Oct 30. http://www.ncbi.nlm.nih.gov/pubmed/23115558
Cardoso AM, Cavalcante JJ, Cantão ME, Thompson CE, Flatschart RB, Glogauer A, Scapin SM, Sade YB, Beltrão PJ, Gerber AL, Martins OB, Garcia ES, de Souza W, Vasconcelos AT. Metagenomic analysis of the microbiota from the crop of an invasive snail reveals a rich reservoir of novel genes. PLoS One. 2012;7(11):e48505. Epub 2012 Nov 1. http://www.ncbi.nlm.nih.gov/pubmed/23133637
Carvalho CM, Silverio JC, da Silva AA, Pereira IR, Coelho JM, Britto CC, Moreira OC, Marchevsky RS, Xavier SS, Gazzinelli RT, da Glória Bonecini-Almeida M, Lannes-Vieira J. Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury. PLoS Negl Trop Dis. 2012 May;6(5):e1644.
Carvalho SA, Feitosa LO, Soares M, Costa TE, Henriques MG, Salomão K, de Castro SL, Kaiser M, Brun R, Wardell JL, Wardell SM, Trossini GH, Andricopulo AD, da Silva EF, Fraga CA. Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents. Eur J Med Chem. 2012 Aug;54:512-21. http://www.sciencedirect.com/science/article/pii/S0223523412003522
Castro DP, Moraes CS, Gonzalez MS, Ratcliffe NA, Azambuja P, Garcia ES. Trypanosoma cruzi immune response modulation decreases microbiota in Rhodnius prolixus gut and is crucial for parasite survival and development. PLoS One. 2012;7(5):e36591. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0036591
Castro DP, Moraes CS, Gonzalez MS, Ribeiro IM, Tomassini TC, Azambuja P, Garcia ES. Physalin B inhibits Trypanosoma cruzi infection in the gut of Rhodnius prolixus by affecting the immune system and microbiota. J Insect Physiol. 2012 Dec;58(12):1620-5. http://www.ncbi.nlm.nih.gov/pubmed/23085484
Cestari I, Evans-Osses I, Schlapbach LJ, de Messias-Reason I, Ramirez MI. Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites. Mol Immunol. 2013 Apr;53(4):328-34. http://www.ncbi.nlm.nih.gov/pubmed/23063472
Cestari I, Ansa-Addo E, Deolindo P, Inal JM, Ramirez MI. Trypanosoma cruzi immune evasion mediated by host cell-derived microvesicles. J Immunol. 2012 Feb 15;188(4):1942-52.
Chiang RG, Chiang JA, Sarquis O, Lima MM. Morphology of reproductive accessory glands in eight species of blood-feeding Hemiptera (Hemiptera, Reduviidae) insect vectors of Chagas disease. Acta Trop. 2012 May;122(2):196-204. http://www.sciencedirect.com/science/article/pii/S0001706X12000125
Cortez MR, Provençano A, Silva CE, Mello CB, Zimmermann LT, Schaub GA, Garcia ES, Azambuja P, Gonzalez MS. Trypanosoma cruzi: effects of azadirachtin and ecdysone on the dynamic development in Rhodnius prolixus larvae. Exp Parasitol. 2012 Jul;131(3):363-71. Epub 2012 May 22. http://www.ncbi.nlm.nih.gov/pubmed/22626520
Coura JR, Junqueira AC. Risks of endemicity, morbidity and perspectives regarding the control of Chagas disease in the Amazon Region. Mem Inst Oswaldo Cruz. 2012 Mar;107(2):145-54. http://www.ncbi.nlm.nih.gov/pubmed/22415251
Coura JR, Borges-Pereira J. Chagas disease. What is known and what should be improved: a systemic review. Rev Soc Bras Med Trop. 2012 Jun;45(3):286-96.
Coutinho CF, Souza-Santos R, Lima MM. Combining geospatial analysis and exploratory study of triatomine ecology to evaluate the risk of Chagas disease in a rural locality. Acta Trop. 2012 Jan;121(1):30-3. http://www.sciencedirect.com/science/article/pii/S0001706X11002907
da Silva Júnior EN, de Melo IM, Diogo EB, Costa VA, de Souza Filho JD, Valença WO, Camara CA, de Oliveira RN, de Araujo AS, Emery FS, dos Santos MR, de Simone CA, Menna-Barreto RF, de Castro SL. On the search for potential anti-Trypanosoma cruzi drugs: Synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions. Eur J Med Chem. 2012 Jun;52:304-12. Epub 2012 Mar 29. http://www.ncbi.nlm.nih.gov/pubmed/22483633
da Mota FF, Marinho LP, Moreira CJ, Lima MM, Mello CB, Garcia ES, Carels N, Azambuja P. Cultivation-independent methods reveal differences among bacterial gut microbiota in triatomine vectors of Chagas disease. PLoS Negl Trop Dis. 2012 May;6(5):e1631. http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001631
da Silva CF, Batista Dda G, Oliveira GM, de Souza EM, Hammer ER, da Silva PB, Daliry A, Araujo JS, Britto C, Rodrigues AC, Liu Z, Farahat AA, Kumar A, Boykin DW, Soeiro Mde N. In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infection. PLoS One. 2012;7(1):e30356. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030356
da Silva DR, de Castro SL, Alves MC, Batista Wda S, de Oliveira GM. Acute experimental Trypanosoma cruzi infection: establishing a murine model that utilises non-invasive measurements of disease parameters. Mem Inst Oswaldo Cruz. 2012 Mar;107(2):211-6.
de Almeida AP, Soares J, Meneses AA, Cardoso SC, Braz D, Garcia ES, Gonzalez MS, Azambuja P, Barroso RC. Phase contrast X-ray synchrotron imaging for assessing external and internal morphology of Rhodnius prolixus. Appl Radiat Isot. 2012 Jul;70(7):1340-3. Epub 2011 Nov 25. http://www.sciencedirect.com/science/article/pii/S096980431100563X
de Oliveira FL, Araújo-Jorge TC, de Souza EM, de Oliveira GM, Degrave WM, Feige JJ, Bailly S, Waghabi MC. GW788388, an inhibitor of transforming growth factor beta signaling, prevents heart fibrosis in Chagas disease. PLoS Negl Trop Dis. 2012 Jun;6(6):e1696.
de Sousa MA, Dos Santos Pereira SM, Dos Santos Faissal BN. Variable sensitivity to complement-mediated lysis among Trypanosoma rangeli reference strains. Parasitol Res. 2012 Feb;110(2):599-608. http://link.springer.com/article/10.1007%2Fs00436-011-2528-8.
Fernandes MC, Da Silva EN, Pinto AV, De Castro SL, Menna-Barreto RF. A novel triazolic naphthofuranquinone induces autophagy in reservosomes and impairment of mitosis in Trypanosoma cruzi. Parasitology. 2012 Jan;139(1):26-36. http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8474029
Ferrão PM, de Oliveira FL, Degrave WM, Araujo-Jorge TC, Mendonça-Lima L, Waghabi MC. A phosphoproteomic approach towards the understanding of the role of TGF-β in Trypanosoma cruzi biology. PLoS ONE 7(6):e38736. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038736
França-Costa J, Wanderley JL, Deolindo P, Zarattini JB, Costa J, Soong L, Barcinski MA, Barral A, Borges VM. Exposure of phosphatidylserine on Leishmania amazonensis isolates is associated with diffuse cutaneous leishmaniasis and parasite infectivity. PLoS One. 2012;7(5):e36595. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0036595
Freitas C, Assis MC, Saliba AM, Morandi VM, Figueiredo CC, Pereira M, Plotkowski MC. The infection of microvascular endothelial cells with ExoU-producing Pseudomonas aeruginosa triggers the release of von Willebrand factor and platelet adhesion. Mem Inst Oswaldo Cruz. 2012 Sep;107(6):728-34. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000600004&lng=en&nrm=iso&tlng=en
Garcia ES, Castro DP, Figueiredo MB, Azambuja P. Parasite-mediated interactions within the insect vector: Trypanosoma rangeli strategies. Parasit Vectors. 2012 May 30;5(1):105. http://www.parasitesandvectors.com/content/pdf/1756-3305-5-105.pdf
Gunatilleke SS, Calvet CM, Johnston JB, Chen CK, Erenburg G, Gut J, Engel JC, Ang KK, Mulvaney J, Chen S, Arkin MR, McKerrow JH, Podust LM. Diverse Inhibitor Chemotypes Targeting Trypanosoma cruzi CYP51. PLoS Negl Trop Dis. 2012 Jul;6(7):e1736. Epub 2012 Jul 31. http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001736
Gurgel-Gonçalves R, Galvão C, Costa J, Peterson AT. Geographic distribution of chagas disease vectors in Brazil based on ecological niche modeling. J Trop Med. 2012;2012:705326. Epub 2012 Feb 27. http://www.ncbi.nlm.nih.gov/pubmed/22523500
Henriques C, Castro DP, Gomes LH, Garcia ES, de Souza W. Bioluminescent imaging of Trypanosoma cruzi infection in Rhodnius prolixus. Parasit Vectors. 2012 Sep 26;5:214. http://www.parasitesandvectors.com/content/5/1/214
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr;8(4):445-544. http://www.landesbioscience.com/journals/autophagy/article/19496/?nocache=1430279533
Lima MM, Sarquis O, de Oliveira TG, Gomes TF, Coutinho C, Daflon-Teixeira NF, Toma HK, Britto C, Teixeira BR, D'Andrea PS, Jansen AM, Bóia MN, Carvalho-Costa FA. Investigation of Chagas disease in four periurban areas in northeastern Brazil: epidemiologic survey in man, vectors, non-human hosts and reservoirs. Trans R Soc Trop Med Hyg. 2012 Mar;106(3):143-9. http://www.sciencedirect.com/science/article/pii/S0035920311002240
Machado FS, Rodriguez NE, Adesse D, Garzoni LR, Esper L, Lisanti MP, Burk RD, Albanese C, Van Doorslaer K, Weiss LM, Nagajyothi F, Nosanchuk JD, Wilson ME, Tanowitz HB. Recent developments in the interactions between caveolin and pathogens. Adv Exp Med Biol. 2012;729:65-82. http://www.springerlink.com/content/mu1xn15261861hl8/
Machado MP, Rocha AM, de Oliveira LF, de Cuba MB, de Oliveira Loss I, Castellano LR, Silva MV, Machado JR, Nascentes GA, Paiva LH, Savino W, Junior VR, Brum PC, Prado VF, Prado MA, Silva EL, Montano N, Ramirez LE, Dias da Silva VJ. Autonomic nervous system modulation affects the inflammatory immune response in mice with acute Chagas disease. Exp Physiol. 2012 Nov;97(11):1186-202. Epub 2012 Jun 15. http://ep.physoc.org/content/97/11/1186.long.
Martins DA, Gouvea LR, da Gama Jean Batista D, da Silva PB, Louro SR, de Nazaré C Soeiro M, Teixeira LR. Copper(II)-fluoroquinolone complexes with anti-Trypanosoma cruzi activity and DNA binding ability. Biometals. 2012 Oct;25(5):951-60. Epub 2012 Jun 10. http://link.springer.com/article/10.1007%2Fs10534-012-9565-3.
Matta Guedes PM, Gutierrez FR, Nascimento MS, Do-Valle-Matta MA, Silva JS. Antiparasitical chemotherapy in Chagas disease cardiomyopathy: current evidence. Trop Med Int Health. 2012 Sep;17(9):1057-65. Epub 2012 Jun 12. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-3156.2012.03025.x/abstract
Morrot A, Barreto de Albuquerque J, Berbert LR, de Carvalho Pinto CE, de Meis J, Savino W. Dynamics of Lymphocyte Populations during Trypanosoma cruzi Infection: From Thymocyte Depletion to Differential Cell Expansion/Contraction in Peripheral Lymphoid Organs. J Trop Med. 2012;2012:747185. http://www.ncbi.nlm.nih.gov/pubmed/22505943
Oliveira FO Jr, Alves CR, Souza-Silva F, Calvet CM, Côrtes LM, Gonzalez MS, Toma L, Bouças RI, Nader HB, Pereira MC. Trypanosoma cruzi heparin-binding proteins mediate the adherence of epimastigotes to the midgut epithelial cells of Rhodnius prolixus. Parasitology. 2012 May;139(6):735-43. Epub 2012 Feb 7. http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8547442
Paiva CN, Feijó DF, Dutra FF, Carneiro VC, Freitas GB, Alves LS, Mesquita J, Fortes GB, Figueiredo RT, Souza HS, Fantappié MR, Lannes-Vieira J, Bozza MT. Oxidative stress fuels Trypanosoma cruzi infection in mice. J Clin Invest. 2012 Jul 2;122(7):2531-42. Epub 2012 Jun 25.
Pérez AR, Morrot A, Berbert LR, Terra-Granado E, Savino W. Extrathymic CD4+CD8+ lymphocytes in Chagas disease: possible relationship with an immunoendocrine imbalance. Ann N Y Acad Sci. 2012 Jul;1262:27-36. http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2012.06627.x/pdf.
Santos Lda S, Torres RM, Machado-de-Assis GF, Bahia MT, Martins HR, Teixeira-Carvalho A, Coelho-Dos-Reis JG, Albajar-Viñas P, Martins-Filho OA, Lana Md. In-house ELISA method to analyze anti-Trypanosoma cruzi IgG reactivity for differential diagnosis and evaluation of Chagas disease morbidity. Rev Soc Bras Med Trop. 2012 Feb;45(1):35-44.
Sarquis O, Carvalho-Costa FA, Toma HK, Georg I, Burgoa MR, Lima MM. Eco-epidemiology of Chagas disease in northeastern Brazil: Triatoma brasiliensis, T. pseudomaculata and Rhodnius nasutus in the sylvatic, peridomestic and domestic environments. Parasitol Res. 2012 Apr;110(4):1481-5. http://www.springerlink.com/content/m75828857523477k/fulltext.pdf
Silverio JC, Pereira IR, Cipitelli Mda C, Vinagre NF, Rodrigues MM, Gazzinelli RT, Lannes-Vieira J. CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy. PLoS Pathog. 2012 Apr;8(4):e1002645. http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002645
Uehara LA, Moreira OC, Oliveira AC, Azambuja P, Lima AP, Britto C, Dos Santos AL, Branquinha MH, d'Avila-Levy CM. Cruzipain Promotes Trypanosoma cruzi Adhesion to Rhodnius prolixus Midgut. PLoS Negl Trop Dis. 2012 Dec;6(12):e1958. http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001958
Vilar-Pereira G, Silva AA, Pereira IR, Silva RR, Moreira OC, de Almeida LR, de Souza AS, Rocha MS, Lannes-Vieira J. Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions. Brain Behav Immun. 2012 Oct;26(7):1136-49. Epub 2012 Jul 25. http://www.sciencedirect.com/science/article/pii/S0889159112001924
Waniek PJ, Pacheco Costa JE, Jansen AM, Costa J, Araújo CA. Cathepsin L of Triatoma brasiliensis (Reduviidae, Triatominae): sequence characterization, expression pattern and zymography. J Insect Physiol. 2012 Jan;58(1):178-87. Epub 2011 Nov 13. http://www.sciencedirect.com/science/article/pii/S0022191011003246
Xavier SC, Roque AL, Lima Vdos S, Monteiro KJ, Otaviano JC, Ferreira da Silva LF, Jansen AM. Lower richness of small wild mammal species and chagas disease risk. PLoS Negl Trop Dis. 2012 May;6(5):e1647. http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001647
Zhu X, Liu Q, Yang S, Parman T, Green CE, Mirsalis JC, de Nazaré Correia Soeiro M, Mello de Souza E, da Silva CF, da Gama Jaen Batista D, Stephens CE, Banerjee M, Farahat AA, Munde M, Wilson WD, Boykin DW, Wang MZ, Werbovetz KA. Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology Studies. Antimicrob Agents Chemother. 2012 Jul;56(7):3690-9. http://aac.asm.org/content/56/7/3690.long
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