Área de PDI em Farmacologia, Fisiopatologia, Inovações Terapêuticas e Bioprodutos 2012
Almeida PE, Carneiro AB, Silva AR, Bozza PT, PPARγ Expression and Function in Mycobacterial Infection: Roles in Lipid Metabolism, Immunity, and Bacterial Killing, 2012, PPAR Research, 2012:383829. http://www.ncbi.nlm.nih.gov/pubmed/22851964
Aquino, PF; Fischer, JS; Neves-Ferreira, AG; Perales, J; Domont, GB; Araujo, GD; Barbosa, VC; Viana, J; Chalub, SR; Lima de Souza, AQ; Carvalho, MG; Leão de Souza, AD & Carvalho, PC. 2012. Are gastric cancer resection margin proteomic profiles more similar to those from controls or tumors? J. Proteome Res., 11 (12): 5836-5842. http://pubs.acs.org/doi/abs/10.1021/pr300612x
Araújo CV, Estato V, Tibiriçá E, Bozza PT, Castro-Faria-Neto HC, Silva AR, PPAR gamma activation protects the brain against microvascular dysfunction in sepsis, 2012, Microvascular Research, Sep; 84(2):218-21. http://www.sciencedirect.com/science/article/pii/S0026286212001082
Barbosa, ML; Ramos, TJ; de Arantes, AC; Martins, MA; Silva, PM; Barreiro, EJ & Lima, LM. 2012. Synthesis and pharmacological evaluation of novel phenyl sulfonamide derivatives designed as modulators of pulmonary inflammatory response. Molecules, 17 (12): 14651-72. http://www.mdpi.com/1420-3049/17/12/14651
Barreto, CF; Vilela, CG; Baptista-Neto, JÁ & Barth, OM. 2012. Spatial distribution of pollen grains and spores in surface sediments of Guanabara Bay, Rio de Janeiro, Brazil. An Acad Bras Cienc. 84 (3): 627-44. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012005000049&lng=en&nrm=iso&tlng=en
Barros, FR; Castro-Faria-Neto, HC; Castro, CL; Aguiar Nemer, AS; Rocha, EM & Silva Fonseca, VA. 2012. Effects of chronic ethanol consumption in experimental sepsis. Alcohol Alcohol. 47 (6): 677-82. http://alcalc.oxfordjournals.org/content/47/6/677.long
Bencze, M; Negroni, E; Vallese, D; Yacoub-Youssef, H; Chaouch, S; Wolff, A; Aamiri, A; Di Santo, JP; Chazaud, B; Butler-Browne, G; Savino, W; Mouly, V & Riederer, I. 2-12. Proinflammatory macrophages enhance the regenerative capacity of human myoblasts by modifying their kinetics of proliferation and differentiation. Mol. Ther., 20 (11): 2168-2179. http://www.nature.com/mt/journal/v20/n11/full/mt2012189a.html
Bernardino AM, Azevedo AR, Pinheiro LC, Borges JC, Paixão IC, Mesquita M, Souza TM, Dos Santos MS, Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridines, 2012, Organic and Medicinal Chemistry Letters, Feb 1;2(1):3. http://www.orgmedchemlett.com/content/2/1/3
Bezerra-Santos CR, Vieira-de-Abreu A, Vieira GC, Filho JR, Barbosa-Filho JM, Pires AL, Martins MA, Souza HS, Bandeira-Melo C, Bozza PT, Piuvezam MR. Effectiveness of Cissampelos sympodialis and its isolated alkaloid warifteine in airway hyperreactivity and lung remodeling in a mouse model of asthma, 2012, International Immunopharmacology, Jun;13(2):148-55. http://www.sciencedirect.com/science/article/pii/S1567576912000872
Braga, JA; Sales, ÉO; Neto, JS; Conde, MM; Barth, MO & Lorenzon, MC. 2012. Floral sources to Tetragonisca angustula (Hymenoptera: Apidae) and their pollen morphology in a Southeastern Brazilian Atlantic Forest. Rev. Biol. Trop., 60 (4): 1491-1501. http://www.ncbi.nlm.nih.gov/pubmed/23342504
Brand GD, Salbo R, Jørgensen TJ, Bloch C Jr, Boeri Erba E, Robinson CV, Tanjoni I, Moura-da-Silva AM, Roepstorff P, Domont GB, Perales J, Valente RH, Neves-Ferreira AG, The interaction of the antitoxin DM43 with a snake venom metalloproteinase analyzed by mass spectrometry and surface plasmon resonance, 2012, Journal of Mass Spectrometry, May;47(5):567-73. http://onlinelibrary.wiley.com/doi/10.1002/jms.2990/abstract;jsessionid=72D999F9FD9261F1B9C8EA92AA8D65B2.d04t02
Budas, G; Costa, HM Jr; Ferreira, JC; Teixeira da Silva Ferreira, A; Perales, J; Krieger, JE; Mochly-Rosen, D & Schechtman, D. 2012. Identification of εPKC targets during cardiac ischemic injury. Circ. J., 76 (6): 1476-1485. https://www.jstage.jst.go.jp/article/circj/76/6/76_CJ-11-1360/_pdf
Carvalho PC, Fischer JS, Xu T, Cociorva D, Balbuena TS, Valente RH, Perales J, Yates JR 3rd, Barbosa VC, Search engine processor: Filtering and organizing peptide spectrum matches, 2012, Proteomics, Apr;12(7):944-9. http://onlinelibrary.wiley.com/doi/10.1002/pmic.201100529/abstract
Carvalho, FA; Carneiro, FA; Martins, IC; Assunção-Miranda, I; Faustino, AF; Pereira, RM; Bozza, PT; Castanho, MA; Mohana-Borges, R; da Poian, AT & Santos, NC. 2012. Dengue virus capsid protein binding to hepatic lipid droplets (LD) is potassium ion dependent and is mediated by LD surface proteins. J Virol., 86 (4): 2096-2108. http://jvi.asm.org/content/86/4/2096.long
Ching AT, Paes Leme AF, Zelanis A, Rocha MM, Furtado Mde F, Silva DA, Trugilho MR, da Rocha SL, Perales J, Ho PL, Serrano SM, Junqueira-de-Azevedo IL, Venomics profiling of Thamnodynastes strigatus unveils matrix metalloproteinases and other novel proteins recruited to the toxin arsenal of rear-fanged snakes, 2012, Journal of Proteome Research, Feb 3;11(2):1152-62. http://pubs.acs.org/doi/abs/10.1021/pr200876c
Coelho, LM; Salluh, JI; Soares, M; Bozza, FA; Verdeal, JC; Castro-Faria-Neto, HC; Lapa, e Silva JR; Bozza, PT & Póvoa, P. 2012. Patterns of c-reactive protein RATIO response in severe community-acquired pneumonia: a cohort study. Crit Care, 16 (2): R53. http://ccforum.com/content/16/2/R53
Comim, CM; Reis, PA; Frutuoso, VS; Fries, GR; Fraga, DB; Kapczinski, F; Zugno, AI; Barichello, T; Quevedo, J & Castro-Faria-Neto, HC. 2012. Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice. Neurosci Lett., 523 (2): 104-7. http://www.sciencedirect.com/science/article/pii/S0304394012008592
Cordovil I, Huguenin G, Rosa G, Bello A, Köhler O, de Moraes R, Tibiriçá E, Evaluation of systemic microvascular endothelial function using laser speckle contrast imaging, 2012, Microvascular Research, May;83(3):376-9. http://www.sciencedirect.com/science/article/pii/S0026286212000052
Crestani J, Carvalho PC, Han X, Seixas A, Broetto L, Fischer Jde S, Staats CC, Schrank A, Yates JR 3rd, Vainstein MH, Proteomic profiling of the influence of iron availability on Cryptococcus gattii, 2012, Journal of Proteome Research, Jan 1;11(1):189-205. http://pubs.acs.org/doi/full/10.1021/pr2005296
de Freitas AD, Vit P, Barth OM, Pollen Profile of Geopropolis Samples Collected by Native Bees (Meliponini) in some South American Countries, 2012, Sociobiology, volume 59, Issue 4, pages 1465-1482. http://www.saber.ula.ve/dspace/bitstream/123456789/36997/1/9_pollen_analysis.pdf
dos Santos RL, Lacerda MCM, Gonçalves RT, Martins MA, Gomes de Souza MM, Immunosuppressants: implications in Orthodontics, 2012, Dental Press Journal of Orthodontics, vol.17 no.2. http://www.scielo.br/scielo.php?pid=S2176-94512012000200012&script=sci_arttext
Faria, R; Ferreira, L; Bezerra, R; Frutuoso, V & Alves, L. 2012. Action of natural products on P2 receptors: A reinvented era for drug discovery. Molecules, 17 (11): 13009-13025. http://www.mdpi.com/1420-3049/17/11/13009
Gandra PG, Valente RH, Perales J, Pacheco AG, Macedo DV, Proteomic analysis of rat skeletal muscle submitted to one bout of incremental exercise, 2012, Scandinavian Journal of Medicine and Science in Sports, Apr;22(2):207-16. http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0838.2010.01235.x/abstract
Gandra, PG; Valente, RH; Perales, J; Pacheco, AG & Macedo, DV. 2012. Proteomic profiling of skeletal muscle in an animal model of overtraining. Proteomics, 12 (17): 2663-2667. http://onlinelibrary.wiley.com/doi/10.1002/pmic.201200137/abstract
Gonçalves de Albuquerque, CF; Burth, P; Younes Ibrahim, M; Garcia, DG; Bozza, PT; Castro Faria Neto, HC & Castro Faria, MV. 2012. Reduced plasma nonesterified fatty acid levels and the advent of an acute lung injury in mice after intravenous or enteral oleic acid administration. Mediators Inflamm, 2012: 601032. http://www.hindawi.com/journals/mi/2012/601032/
Gonçalves-de-Albuquerque, CF; Burth, P; Silva, AR; Younes-Ibrahim, M; Castro-Faria-Neto, HC & Castro-Faria, MV. 2012. Leptospira and inflammation. Mediators Inflamm., 2012:317950. http://www.hindawi.com/journals/mi/2012/317950/
Gonçalves-de-Albuquerque, CF; Silva, AR; Burth, P; de Moraes, IM; Oliveira, FM; Younes-Ibrahim, M; Dos Santos, M da C; D'Ávila, H; Bozza, PT; Faria Neto, HC & de Castro Faria, MV. 2012. Oleic Acid Induces Lung Injury in Mice through Activation of the ERK Pathway. Mediators Inflamm, 2012: 956509. http://www.hindawi.com/journals/mi/2012/956509/
Jones CF, Campbell RA, Franks Z, Gibson CC, Thiagarajan G, Vieira-de-Abreu A, Sukavaneshvar S, Mohammad SF, Li DY, Ghandehari H, Weyrich AS, Brooks BD, Grainger DW., Cationic PAMAM dendrimers disrupt key platelet functions, 2012, Molecular Pharmaceutics, Jun 4;9(6):1599-611. http://www.ncbi.nlm.nih.gov/pubmed/22497592
Kümmerle, AE; Schmitt, M; Cardozo, SV; Lugnier, C; Villa, P; Lopes, AB; Romeiro, NC; Justiniano, H; Martins, MA; Fraga, CA; Bourguignon, JJ & Barreiro, EJ. 2012. Design, synthesis, and pharmacological evaluation of N-acylhydrazones and novel conformationally constrained compounds as selective and potent orally active phosphodiesterase-4 inhibitors. J Med Chem., 55 (17): 7525-45. 2012. http://pubs.acs.org/doi/abs/10.1021/jm300514y
Lachtermacher, S; Esporcatte, BL; Fortes, F da S; Rocha, NN; Montalvão, F; Costa, PC; Belem, L; Rabischoffisky, A; Faria Neto, HC; Vasconcellos, R; Iacobas, DA; Iacobas, S; Spray, DC; Thomas, NM; Goldenberg, RC & de Carvalho, AC. 2012. Functional and transcriptomic recovery of infarcted mouse myocardium treated with bone marrow mononuclearcells. Stem Cell Rev., 8 (1): 251-261. http://link.springer.com/article/10.1007%2Fs12015-011-9282-2
Lanzetti, M; da Costa, CA; Nesi, RT; Barroso, MV; Martins, V; Victoni, T; Lagente, V; Pires, KM; e Silva, PM; Resende, AC; Porto, LC; Benjamim, CF & Valença, SS. 2012. Oxidative stress and nitrosative stress are involved in different stages of proteolytic pulmonary emphysema. Free Radic Biol Med, 53 (11): 1993-2001. http://www.sciencedirect.com/science/article/pii/S0891584912011409
León, IR; Neves-Ferreira, AG; da Rocha, SL; Trugilho, MR; Perales, J & Valente, RH. 2012. Using mass spectrometry to explore the neglected glycan moieties of the antiophidic proteins DM43 and DM64. Proteomics. 12 (17): 2753-65. http://onlinelibrary.wiley.com/doi/10.1002/pmic.201200062/abstract
Lepletier, A; de Frias Carvalho, V; Morrot, A & Savino, W. 2012. Thymic atrophy in acute experimental Chagas disease is associated with an imbalance of stress hormones. Ann. N Y Acad. Sci., 1262: 45-50. http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2012.06601.x/abstract
Lima VL, Dias F, Nunes RD, Pereira LO, Santos TS, Chiarini LB, Ramos TD, Silva-Mendes BJ, Perales J, Valente RH, Oliveira PL, The antioxidant role of xanthurenic acid in the Aedes aegypti midgut during digestion of a blood meal, 2012, PLoS One, 7(6):e38349. http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038349
Machado, CC; Nojima, M da C; Rodrigues e Silva, PM & Mandarim-de-Lacerda, CA. 2012. Histomorphometric study of the periodontal ligament in the initial period of orthodontic movement in Wistar rats with induced allergic asthma. Am J Orthod Dentofacial Orthop., 142 (3): 333-8. 2012. http://www.sciencedirect.com/science/article/pii/S088954061200488X
Maracajá-Neto, LF; Mello Silva, GA; de Moura, RS; Tibiriçá, E & Lessa, MA. 2012. Opioid receptor blockade prevents propofol-induced hypotension in rats. J Neurosurg Anesthesiol, 24 (3): 191-6. http://www.ncbi.nlm.nih.gov/pubmed/22314307
Martins IC, Gomes-Neto F, Faustino AF, Carvalho FA, Carneiro FA, Bozza PT, Mohana-Borges R, Castanho MA, Almeida FC, Santos NC, Da Poian AT, The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif, 2012, The Biochemical Journal, Jun 15;444(3):405-15. http://www.biochemj.org/bj/444/0405/bj4440405.htm
Mello, R da S; Borja, GE & Queiroz, MM. 2012. How photoperiods affect the immature development of forensically important blowfly species Chrysomya albiceps (Calliphoridae). Parasitol Res., 111 (3): 1067-73. http://link.springer.com/article/10.1007%2Fs00436-012-2933-7
Olsen, PC; Coelho, LP; da Costa, JC; Cordeiro, RS; Silva, PM & Martins, MA. 2012. Two for one: cyclic AMP mediates the anti-inflammatory and anti-spasmodic properties of the non-anesthetic lidocaine analog JMF2-1. Eur J Pharmacol, 680 (1-3): 102-7. http://www.sciencedirect.com/science/article/pii/S0014299912001100
Pacheco, GJ; Reis, RS; Fernandes, AC; da Rocha, SL; Pereira, MD; Perales, J & Freire, DM. 2012. Rhamnolipid production: effect of oxidative stress on virulence factors and proteome of Pseudomonas aeruginosa PA1. Appl Microbiol Biotechnol, 95 (6): 1519-29. http://link.springer.com/article/10.1007%2Fs00253-012-4258-y
Pinto da Luz CF, Barth OM, Pollen analysis of honey and beebread derived from Brazilian mangroves, 2012, Brazilian Journal of Botany, vol.35 no.1 http://www.scielo.br/pdf/rbb/v35n1/a09v35n1.pdf
Rebello, KM; de Siqueira, CR; Ribeiro, EL; Valente, RH; Mota, EM; Perales, J; Neves-Ferreira, AG & Lenzi, HL. 2012. Proteolytic activity in the adult and larval stages of the human roundworm parasite Angiostrongylus costaricensis. Mem Inst Oswaldo Cruz, 107 (6): 752-9. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000600008&lng=en&nrm=iso&tlng=en
Reis, PA; Estato, V; da Silva, TI; d'Avila, JC; Siqueira, LD; Assis, EF; Bozza, PT; Bozza, FA; Tibiriça, EV; Zimmerman, GA & Castro-Faria-Neto, HC. 2012. Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria. PLoS Pathog., 8 (12): e1003099. http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1003099
Reis Gonçalves, CT; Reis Gonçalves, CG; de Almeida, FM; dos Santos Lopes, FD; dos Santos Durão, AC; dos Santos, FA; da Silva, LF; Marcourakis, T; Castro-Faria-Neto, HC; Vieira, RD & Dolhnikoff, M. 2012. Protective effects of aerobic exercise on acute lung injury induced by LPS in mice. Crit Care, 16 (5): R199. http://ccforum.com/content/16/5/R199
Santos SG, Diniz CG, Silva VL, Lima FL, Andrade HM, Chapeaurouge DA, Perales J, Serufo JC, Carvalho MA, Farias LM, Differentially regulated proteins in Prevotella intermedia after oxidative stress analyzed by 2D electrophoresis and mass spectrometry, 2012, Anaerobe, Feb;18(1):76-82. http://www.sciencedirect.com/science/article/pii/S1075996411002290
Schmidt TJ, Khalid SA, Romanha AJ, Alves TM, Biavatti MW, Brun R, Da Costa FB, de Castro SL, Ferreira VF, de Lacerda MV, Lago JH, Leon LL, Lopes NP, das Neves Amorim RC, Niehues M, Ogungbe IV, Pohlit AM, Scotti MT, Setzer WN, de N C Soeiro M, Steindel M, Tempone AG. The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - Part II. Curr Med Chem. 2012;19(14):2176-228. http://www.eurekaselect.com/97284/article
Schmidt TJ, Khalid SA, Romanha AJ, Alves TM, Biavatti MW, Brun R, Da Costa FB, de Castro SL, Ferreira VF, de Lacerda MV, Lago JH, Leon LL, Lopes NP, das Neves Amorim RC, Niehues M, Ogungbe IV, Pohlit AM, Scotti MT, Setzer WN, de N C Soeiro M, Steindel M, Tempone AG. The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases – Part I. Curr Med Chem. 2012;19(14):2128-75. http://www.eurekaselect.com/97283/article
Serra, MF; Anjos-Valotta, EA; Olsen, PC; Couto, GC; Jurgilas, PB; Cotias, AC; Pão, CR; Ferreira, TP; Arantes, AC; Pires, AL; Cordeiro, RS; Silva, PM & Martins, MA. 2012. Nebulized lidocaine prevents airway inflammation, peribronchial fibrosis, and mucus production in a murine model of asthma. Anesthesiology, 117 (3): 580-91. http://www.ncbi.nlm.nih.gov/pubmed/22846675
Silva, EC; Masui, DC; Furriel, RP; McNamara, JC; Barrabin, H; Scofano, HM; Perales, J; Teixeira-Ferreira, A; Leone, FA & Fontes, CF. 2012. Identification of a crab gill FXYD2 protein and regulation of crab microsomal Na,K-ATPase activity by mammalian FXYD2 peptide. Biochim Biophys Acta, 1818 (11): 2588-2597. http://www.sciencedirect.com/science/article/pii/S0005273612001678
Soares, JR; de Oliveira Carvalho, A; dos Santos, IS; Machado, OL; Nascimento, VV; Vasconcelos, IM; da Silva Ferreira, AT; de Aguilar Perales, JE & Gomes, VM. 2012. Antimicrobial peptides from Adenanthera pavonina L. seeds: characterization and antifungal activity. Protein Pept Lett., 19 (5): 520-529. http://www.eurekaselect.com/96616/article
Souza AJ, Ferreira AT, Perales J, Beghini DG, Fernandes KV, Xavier-Filho J, Venancio TM, Oliveira AE, Identification of Albizia lebbeck seed coat chitin-binding vicilins (7S globulins) with high toxicity to the larvae of the bruchid Callosobruchus maculates, 2012, Brazilian Journal Medical and Biology Research, Feb;45(2):118-24. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012007500008&lng=en&nrm=iso&tlng=en
Souza, CO; Santoro, GF; Figliuolo, VR; Nanini, HF; de Souza, HS; Castelo-Branco, MT; Abalo, AA; Paiva, MM; Coutinho, CM & Coutinho-Silva, R. 2012. Extracellular ATP induces cell death in human intestinal epithelial cells. Biochim Biophys Acta, 1820 (12): 1867-78. http://www.sciencedirect.com/science/article/pii/S0304416512002334
Sperandei, S. 2012. Comment on: Hegde et al. Effect of 3-Month Yoga on Oxidative Stress in Type 2 Diabetes With or Without Complications: A Controlled Clinical Trial. Diabetes Care 2011; 34: 2208–2210. Diabetes Care, 35: e42. http://care.diabetesjournals.org/content/35/6/e42.full.pdf+html
Teixeira, CMLL; Kirsten, FV & Teixeira, PCN. 2012. Evaluation of Moringa oleifera seed flour as a flocculating agent for potential biodiesel producer microalgae. J. Appl. Phycol., 24: 557–563. http://link.springer.com/content/pdf/10.1007%2Fs10811-011-9773-1.pdf
Torres, RC; Batista, MM; Pons, AH; Silva, AR; Cordeiro, RS; Martins, MAE; Silva, PM & Carvalho, VF. 2012. Activation of PPARγ by restores mast cell numbers and reactivity in alloxan-diabetic rats by reducing the systemic glucocorticoid levels. Eur J Pharmacol., 691 (1-3): 261-267. http://www.sciencedirect.com/science/article/pii/S0014299912005225
Vieira-de-Abreu A, Campbell RA, Weyrich AS, Zimmerman GA., Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum, 2012, Seminars in Immunopathology, Jan;34(1):5-30. http://www.ncbi.nlm.nih.gov/pubmed/21818701
Vieira Rde P, Toledo AC, Silva LB, Almeida FM, Damaceno-Rodrigues NR, Caldini EG, Santos AB, Rivero DH, Hizume DC, Lopes FD, Olivo CR, Castro-Faria-Neto HC, Martins MA, Saldiva PH, Dolhnikoff M, Anti-inflammatory effects of aerobic exercise in mice exposed to air pollution, 2012, Medicine and Science in Sports and Exercise, Jul;44(7):1227-34. http://www.ncbi.nlm.nih.gov/pubmed/22297803
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Werneck, MB; Hottz, E; Bozza, PT 7 Viola, JP. 2012. Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway. Cell Cycle, 11 (21): 3997-4008. http://www.landesbioscience.com/journals/cc/article/22222/
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