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ARTIGOS CIENTÍFICOS

Confira a lista dos artigos publicados em periódicos indexados pelos pesquisadores do Laboratório de Imunofarmacologia do Instituto Oswaldo Cruz (IOC/Fiocruz):

2014

Indexado (fator de impacto < 1 ou sem FI)

Gonçalves CF, Burth Patrícia, Silva AR, Medeiros-de-Moraes IM, Oliveira FMJ, Santelli Erthal Ricardo, Freire Soares Aline, Younes-Ibrahim Mauricio, Castro-Faria-Neto HC, de Castro-Faria Velho Mauro 2014. Na/K-ATPase assay in the intact mice lung subjected to perfusion. BMC Res Notes 7: - .
Carvalho GM, Nagato LKS, Fagundes S, Santos FB, Calheiros AS, Malm O, Bozza PT, Saldiva PH, Faffe S D , Rocco PR., Zin W A 2014. Time course of pulmonary burden in mice exposed to residual oil fly ash. Front Physiol 5: - .

Indexado (fator de impacto >= 7,51)

Nascimento EJ, Hottz ED, Garcia-Bates TM, Bozza F.A., Marques ET Jr, Barratt-Boyes SM 2014. Emerging Concepts in Dengue Pathogenesis: Interplay between Plasmablasts, Platelets and Complement in Triggering Vasculopathy. Crit Rev Biotechnol 34: 227-240.

Indexado (fator de impacto >=1 e < 2,71)

Miranda Mota L A, Neto JR, Monteiro VG, Lobato C S S , Oliveira M, Cunha M, DÁvila H, Seabra HS, Bozza PT, DaMatta R A 2014. Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole and decrease their microbicidal capacity against Toxoplasma gondii. Mem I Oswaldo Cruz 6: 767-774.

Leite FC, Ribeiro Filho J, Costa HF, Salgado PR, Calheiros AS, Carneiro AB, de Almeida RN, Dias Cda S, Bozza PT, Piuvezam MR 2014. Curine, an Alkaloid Isolated from Chondrodendron platyphyllum Inhibits Prostaglandin E2 in Experimental Models of Inflammation and Pain. Planta Med 13: 1072-1078.

Vicente PR, Ritt K, Gonçalves CF, Castro-Faria-Neto HC, Paes-de-Carvalho R, Giestal-de-Araujo E 2014. IL-6, A1 and A2aR: a crosstalk that modulates BDNF and induces neuroprotection. Biochem Bioph Res Co 449: 477-482.

Silva VR, Marcondes P, Silva M, Villaverde AB,, Castro-Faria-Neto HC, Vieira RP, Aimbire F, de Oliveira AP 2014. Low-level laser therapy inhibits bronchoconstriction, Th2 inflammation and airway remodeling in allergic asthma. Resp Physiol Neurobi 1: 34-48.

de Andrade JA, Gayer CR, Nogueira NP, Paes MC, Bastos VL, Neto Jda C, Alves SC Jr,, Coelho RM, Cunha MGAT, Gomes RN, Aguila MB, Mandarim-de-Lacerda CA, Bozza PT, da Cunha S. 2014. The effect of thiamine deficiency on inflammation, oxidative stress and cellular migration in an experimental model of sepsis.. J Inflamm Lond 24: - .

Indexado (fator de impacto >=2,71 e < 4,35)

Ribeiro Filho J, Leite FC2, da Costa HF, Calheiros AS, Torres RC, de Azevedo CT, Martins MA, da Silva Dias C, Bozza PT, Piuvezam MR 2014. Curine inhibits mast cell-dependent responses in mice. J Ethnopharmacol 155(2): 1118-1124.

Miyazaki Y, Adriana, Vieira-de-Abreu A, Harris ES, Weyrich AS, Castro-Faria-Neto HC, Zimmerman GA 2014. Integrin αDβ2 (CD11d/CD18) Is Expressed by Human Circulating and Tissue Myeloid Leukocytes and Mediates Inflammatory Signaling. PLoS One 21: - .

Gonçalves CF, Burth P, Silva AR, Medeiros-de-Moraes IM, Oliveira FMJ, Santelli RE, Freire AS, de Lima GS, da Silva EDS, da Silva CI, Morandi V, Bozza PT, Castro-Faria-Neto HC, de Castro Faria MV 2014. Murine lung injury caused by Leptospira interrogans glycolipoprotein, a specific Na/K-ATPase inhibitor. Resp Res 14: - .

Luna-Gomes T, Filardy AA, Rocha JD, Decote-Ricardo D, Larocque-de-Freitas IF, Morrot A, Bozza PT, Castro-Faria-Neto HC, Dosreis GA, Nunes MP, Freire-de-Lima CG 2014. Neutrophils increase or reduce parasite burden in Trypanosoma cruzi-infected macrophages, depending on host strain: role of neutrophil elastase.. PLoS One 5: - .

Théo Araújo-Santos, Prates D, França-Costa J, Luz NF, Andrade BB, Miranda J, Brodskyn CI, Barral A, Bozza PT, Borges VM 2014. Prostaglandin E 2 /Leukotriene B 4 balance induced by Lutzomyia longipalpis saliva favors Leishmania infantum infection. Parasite Vector 20: - .

Gomes AF, Magalhães KG, Rodrigues RM, de Carvalho L, Coelho RM, Bozza PT, Barbosa HS 2014. Toxoplasma gondii-skeletal muscle cells interaction increases lipid droplet biogenesis and positively modulates the production of IL-12, IFN-g and PGE2. Parasite Vector 23: - .

Indexado (fator de impacto >=4,35 e < 7,51)

Nisimura LM, Estato V, Souza EM, Reis PA, Lessa MA, Castro-Faria-Neto HC, Pereira MCS, Tibiriçá EV, Garzoni LR 2014. Acute Chagas disease induces cerebral microvasculopathy in mice. PLoS Neglect Trop D 8: - .

Silva JD, Paredes BD, Araújo IM, Lopes-Pacheco M, Oliveira MV, Suhett GD,, Faccioli LA,, Assis EF, Castro-Faria-Neto HC, Goldenberg RC, Capelozzi VL, Morales MM, Pelosi P, Xisto DG, Rocco PR. 2014. Effects of Bone Marrow-Derived Mononuclear Cells From Healthy or Acute Respiratory Distress Syndrome Donors on Recipient Lung-Injured Mice. Crit Care Med 42: 510-524.

Antunes-de-Matos K, Oliveira VC, Berrêdo-Pinho M,, Amaral JJ, Antunes LC, Melo RC, Acosta CC,, Moura DF, Olmo R, Han J, Rosa PS, Almeida PE, Christoph H. Borchers, B. Brett Finlay, Sarno EN, Bozza PT, Atella GC, Pessolani MCV 2014. Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment. Cell Microbiol 16: 797-815.

Hottz ED, Medeiros-de-Moraes IM, Vieira-de-Abreu A, Edson F. de Assis, Vals-de-Souza R, Castro-Faria-Neto HC, Weyrich AS, Zimmerman GA, Bozza FA, Bozza PT 2014. Platelet Activation and Apoptosis Modulate Monocyte Inflammatory Responses in Dengue.. J Immunol 11: 1-10.

Araújo-Santos T, Rodríguez NE, Moura-Pontes S, Dixt UG, Abánades DR, Bozza PT, Wilson ME, Borges VM 2014. Role of Prostaglandin F2α Production in Lipid Bodies From Leishmania infantum chagasi: Insights on Virulence.. J Infect Dis 15: 1951-1961.

Hernandes MS, D´avila JCP, Trevelin SC,, Reis PA, Kinjo ER, , Lopes LR, Castro-Faria-Neto HC, Cunha FQ, BOZZA FA 2014. The role of Nox2-derived ROS in the development of cognitive impairment after sepsis. J Neuroinflamm 11: - .

Tavares NM, Araújo-Santos T, Afonso L, Nogueira PM, Lopes UG, Soares RP, Bozza PT, Bandeira-Melo C., Borges VM, Brodskyn C 2014. Understanding the mechanisms controlling Leishmania amazonensis infection in vitro: the role of LTB4 derived from human neutrophils. J Infect Dis 15: 656-666.

2013

Indexado (fator de impacto < 1 ou sem FI)

Luna-Gomes T, Bozza PT, Bandeira-Melo C 2013. Eosinophil recruitment and activation: the role of lipid mediators. Front Pharmacol 4: - .

de Sousa PA,, Vaisman M, Carneiro JR, Guimarães L, Freitas H, Pinheiro MF, Liechocki S, Monteiro CMM, Teixeira Pde F 2013. Prevalence of goiter and thyroid nodular disease in patients with class III obesity. Arq Bras Endocrinol 57: 120-125.

Indexado (fator de impacto >= 7,51)

Hottz ED, Lopes JF, Freitas C, Valls-de-Souza R, Oliveira MF, Bozza MT, Da Poian AT, Weyrich AS, , Zimermman G, Bozza FA, Bozza PT 2013. Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation.. Blood 122: 3405-3414.

Indexado (fator de impacto >=1 e < 2,71)

Gomes RN, Teixeira-Cunha MG, Figueiredo RT, Almeida PE, Alves SC, Bozza PT, Bozza FA, Bozza MT, Zimmerman GA, Castro-Faria-Neto HC 2013. Bacterial clearance in septic mice is modulated by MCP-1/CCL2 and nitric oxide. Shock 39: 63-69.

Bozza FA, D´avila JCP, Cristiane Ritter, Romain Sonneville , Tarek Sharshar, Felipe Dal-Pizzol 2013. Bioenergetics mitochondrial dysfunction, and oxidative stress in the pathophysiology of septic encephalopathy. Shock 39: 10-16.

de Lima FM, Albertini R, Dantas Y, Maia-Filho AL, Santana Cde L, Castro-Faria-Neto HC, França C, Villaverde AB,, Aimbire F 2013. Low-level laser therapy restores the oxidative stress balance in acute lung injury induced by gut ischemia and reperfusion.. Photochem Photobiol 1: 179-188.

Santos RS, Silva PL, de Oliveira GP, Santos CL, Santos CL, Assis EF, Castro-Faria-Neto HC, Capelozzi VL, Morales MM, Pelosi P, Gattass CR, Rocco PR 2013. Oleanolic acid improves pulmonary morphofunctional parameters in experimental sepsis by modulating oxidative and apoptotic processes.. Resp Physiol Neurobi 1: 484-490.

Gonçalves CF, Burth P, Silva AR, Medeiros-de-Moraes  IM, Oliveira FMJ, Santelli RE, Aline Soares Freire, Bozza PT, Younes-Ibrahim M, Castro-Faria-Neto HC, de Castro-Faria MV. 2013. Oleic acid inhibits lung Na/K-ATPase in mice and induces injury with lipid body formation in leukocytes and eicosanoid production.. J Inflamm 10: - .

Indexado (fator de impacto >=2,71 e < 4,35)

Carvalho V, Fernandes L, Conde T, Zamith H, Silva R, Surrage A, Frutuoso V, Castro-Faria-Neto HC, Amendoeira F 2013. Antinociceptive activity of Stephanolepis hispidus skin aqueous extract depends partly on opioid system activation. Mar Drugs 11: 1221-1234.

Ribeiro Filho J, Calheiros AS, Abreu AV, de Carvalho KI, Diego Silva Mendes, Melo CB, , Martins MA, da Silva Dias C, Piuvezam MR, Bozza PT 2013. Curine inhibits eosinophil activation and airway hyper-responsiveness in a mouse model of allergic asthma.. Toxicol Appl Pharmacol 273: 16-19.

Gutierrez TM, Castro-Faria-Neto HC 2013. Insult -dependent effect of bone marrow cell therapy on inflammatory response in a murine model of extra pulmonary acute respiratory distress syndrome. Stem Cell Res Ther 4: - .

Carneiro AB, Bruna Maria Ferreira Iaciura, Lilian Lie Nohara, Carla Duque Lopes, Esteban Mauricio Cordero Veas, Vania Sammartino Mariano, Bozza PT, Ulisses Gazos Lopes, Georgia Correa Atella, Igor Correia Almeida, Mário Alberto Cardoso Silva-Neto 2013. Lysophosphatidylcholine Triggers TLR2- and TLR4- Mediated Signaling Pathways but Counteracts LPS- Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-êB Translocation and MAPK/ERK Phosphorylation. PLoS One 8: - .

Amâncio RT, Japiassu A M , Gomes RN, Mesquita EC, Assis EF, Denise M. Medeiros, Beatriz Grinsztejn, Bozza PT, Castro-Faria-Neto HC, Bozza FA 2013. The Innate Immune Response in HIV/AIDS Septic Shock Patients: A Comparative Study. PLoS One 8: - .

Indexado (fator de impacto >=4,35 e < 7,51)

D´avila JCP, Castro-Faria-Neto HC, R Rodrigues, M Oliveira, Bozza F 2013. Bioenergetic imbalance and oxidative stress in the pathophysiology of septic encephalopathy. Crit Care 17: - .

Hottz ED, Oliveira MF, Nunes PC, Nogueira RM, Valls-de-Souza R, Da Poian AT, Weyrich AS, Zimermman G, Bozza PT, Bozza FA 2013. Dengue induces platelet activation, mitochondrial dysfunction and cell death through mechanisms that involve DC-SIGN and caspases. J Thromb Haemost 11: 951-962.

Gonçalves-de-Almeida CJ, Jasmin JF, Del Galdo F, Lisanti MP 2013. Genetic ablation of caveolin-2 sensitizes mice to bleomycin-induced injury. Cell Cycle 12: 2248-2254.

Towner RA, Garteiser P, Bozza F A, Smith N, Saunders D, D´avila JCP, Oliveira FMJ, Oliveira MF, Ehrenshaft M, Lupu F, Silasi-Mansat R, Ramirez DC, Gomez-Mejiba , Mason RP, Castro-Faria-Neto HC 2013. In vivo detection of free radicals in mouse septic encephalopathy using molecular MRI and immuno-spin trapping. Free Radical Bio Med 23;65C: 828-837.

Amaral JJ, Luis Caetano M. Antunes, Cristiana S. de Macedo, Mattos A K, Jun Han, Jingxi Pan, Andre L. P. Candea, Maria das Graças M. O. Henriques, Marcelo Ribeiro-Alves, Christoph H. Borchers, Sarno EN, Bozza PT, B. Brett Finlay, Pessolani MCV 2013. Metabonomics Reveals Drastic Changes in Anti-Inflammatory/Pro-Resolving Polyunsaturated Fatty Acids-Derived Lipid Mediators in Leprosy Disease. PLoS Neglect Trop D 7: - .

Franks Z, Campbell RA, Abreu AV, Holloway JT, Marvin JE, Kraemer BF, Zimmerman GA, Weyrich AS, , Weyrich AS, 2013. Methicillin-resistant Staphylococcus aureus-induced thrombo-inflammatory response is reduced with timely antibiotic administration. Thromb Haemostasis 109: 684-695.

Floyd RA, Castro-Faria-Neto HC, Zimmerman GA, Hensley K, Towner RA 2013. Nitrone-based therapeutics for neurodegenerative diseases: Their use alone or in combination with lanthionines.. Free Radical Bio Med 13: 43-49.

2012

Indexado (fator de impacto < 1 ou sem FI)
Vieira RD, Toledo AC, Silva LB, Almeida FM, Damaceno-Rodrigues NR, Caldini EG, Santos AB, Rivero DH, Hizume DC, Lopes FD, Olivo CR, Castro-Faria-Neto HC, Martins MA, Saldiva PH, Dolhnikoff M 2012. Anti-inflammatory effects of aerobic exercise in mice exposed to air pollution. Med Sci Sports Exerc 44: 1227-1234.

Indexado (fator de impacto >= 7,51)
Reis PA, Estato V, da Silva T, d´Avila JC, Siqueira LD, Assis EF, Bozza PT, Bozza FA, Tibiriça EV, Zimmermam GA, Castro-Faria-Neto HC 2012. Statins decrease neuroinflammation and prevent cognitive impairment after cerebral malaria. PLoS Pathog 8: - .

Indexado (fator de impacto >=1 e < 2,71)
Faria R, Ferreira L, Bezerra R, Frutuoso V, Alves L 2012. Action of natural products on P2 receptors: A reinvented era for drug discovery. Molecules 17: 13009-13025  GRÁTIS 13009-13025 .

Torres RC, Batista MM, Pons AH, Silva AR, Cordeiro RS, Martins MA, E Silva PM, Carvalho VF 2012. Activation of PPARγ by restores mast cell numbers and reactivity in alloxan-diabetic rats by reducing the systemic glucocorticoid levels. Eur J Pharmacol 691: 261-267.

de Mattos KA, Sarno EN, Pessolani MC, Bozza PT 2012. Deciphering the contribution of lipid droplets in leprosy: multifunctional organelles with roles in Mycobacterium leprae pathogenesis. Mem Inst Oswaldo Cruz 107 Suppl 1: 156-166.

Bezerra-Santos CR, Vieira-de-Abreu A, Vieira GC, Filho JR, Barbosa-Filho JM, Pires AL, Martins MA, Souza HS, Bandeira-Melo C, Bozza PT, Piuvezam MR 2012. Effectiveness of Cissampelos sympodialis and its isolated alkaloid warifteine in airway hyperreactivity and lung remodeling in a mouse model of asthma. Int Immunopharmacol 13: 148-155.

Comim CM, Reis PA, Frutuoso VS, Fries GR, Fraga DB, Kapczinski F, Zugno AI, Barichello T, Quevedo J, Castro-Faria-Neto HC 2012. Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice. Neurosci Lett 523: 104-107.

Almeida PE, Carneiro AB, Silva AR, Bozza PT 2012. PPARγ expression and function in mycobacterial infection: roles in lipid metabolism, immunity, and bacterial killing. PPAR Res 2012: - .

Indexado (fator de impacto >=2,71 e < 4,35)
Jones CF, Campbell RA, Franks Z, Gibson CC, Thiagarajan G, Vieira-de-Abreu A, Sukavaneshvar S, Mohammad SF, Li DY, Ghandehari H, Weyrich AS, Brooks BD, Grainger DW 2012. Cationic PAMAM dendrimers disrupt key platelet functions. Mol Pharm 9: 1599-1611.

Barros FR, Castro-Faria-Neto HC, Castro CL, Aguiar Nemer AS, Rocha EM, Silva Fonseca VA 2012. Effects of chronic ethanol consumption in experimental sepsis. Alcohol Alcohol 47: 677-682.

Werneck MB 2012. Endogenous anticancer mechanism: differentiation. Front Biosci 4: 1518-1538.

Lachtermacher S, Esporcatte BL, Fortes FS, Rocha NN, Montalvão F, Costa PC, Belem L, Rabischoffisky A, Faria Neto HC, Vasconcellos R, Iacobas DA, Iacobas S, Spray DC, Thomas NM, Goldenberg RC, de Carvalho AC 2012. Functional and transcriptomic recovery of infarcted mouse myocardium treated with bone marrow mononuclear cells. Stem Cel Rev 8: 251-261.

Gonçalves-de-Albuquerque CF, Burth P, Silva AR, Younes-Ibrahim M, Castro-Faria-Neto HC, Castro-Faria MV 2012. Leptospira and inflammation. Mediators Inflamm 2012: - .

Gonçalves-de-Albuquerque CF, Silva AR, Burth P, de Moraes IM, Oliveira FM, Younes-Ibrahim M, dos Santos MC, D´Ávila H, Bozza PT, Faria-Neto HC, de Castro Faria MV 2012. Oleic acid induces lung injury in mice through activation of the ERK pathway. Mediators Inflamm 2012: - .

Araújo CV, Estato V, Tibiriçá EV, Bozza PT, Castro-Faria-Neto HC, Silva AR 2012. PPAR gamma activation protects the brain against microvascular dysfunction in sepsis. Microvasc Res 84: 218-221.

Gonçalves de Albuquerque CF, Burth P, Younes Ibrahim M, Garcia DG, Bozza PT, Castro Faria Neto HC, Castro Faria MV 2012. Reduced plasma nonesterified fatty acid levels and the advent of an acute lung injury in mice after intravenous or enteral oleic acid administration. Mediators Inflamm 2012: - .

Indexado (fator de impacto >=4,35 e < 7,51)
Werneck MB, Hottz E, Bozza PT, Viola JP 2012. Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway. Cell Cycle 11: 3997-4008.

Carvalho FA, Carneiro FA, Martins IC, Assunção-Miranda I, Faustino AF, Pereira RM, Bozza PT, Castanho MA, Mohana-Borges R, Da Poian AT, Santos NC 2012. Dengue virus capsid protein binding to hepatic lipid droplets (LD) is potassium ion dependent and is mediated by LD surface proteins. J Virol 86: 2096-2108.

Coelho LM, Salluh JI, Soares M, Bozza F, Verdeal JC, Castro-Faria-Neto HC, Lapa e Silva JR, Bozza PT, Povoa P 2012. Patterns of C-reactive protein ratio response in severe community-acquired pneumonia: a cohort study. Crit Care 16: - .

Vieira-de-Abreu A, Campbell RA, Weyrich AS, Zimmerman GA 2012. Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum. Semin Immunopathol 34: 5-30.

Goncalves CT, Goncalves CG, de Almeida FM, Lopes FD, Durao AC, dos Santos FA, da Silva LF, Marcourakis T, Castro-Faria-Neto HC, Viera RP, Dolhnikoff M 2012. Protective effects of aerobic exercise on acute lung injury induced by LPS in mice. Crit Care 16: - .

Martins IC, Gomes-Neto F, Faustino AF, Carvalho FA, Carneiro FA, Bozza PT, Mohana-Borges R, Castanho MA, Almeida FC, Santos NC, Da Poian AT 2012. The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif. Biochem J 444: 405-415.

2011

<> De Lima FM, Moreira LM, Villaverde AB, Albertini R, Castro-Faria-Neto HC, Aimbire F. Low-level laser therapy (LLLT) acts as cAMP-elevating agent in acute respiratory distress syndrome. Lasers Med Sci. 2011; 26:389–400

<> Japiassú AM, Santiago AP, d'Avila Jda C, Garcia-Souza LF, Galina A, Castro Faria-Neto HC, Bozza FA, Oliveira MF. Bioenergetic failure of human peripheral blood monocytes in patients with septic shock is mediated by reduced F1Fo adenosine-5'-triphosphate synthase activity. Crit Care Med. 2011 May;39(5):1056-1063.

<> Mattos KA, Lara FA, Oliveira VG, Rodrigues LS, D'Avila H, Melo RC, Manso PP, Sarno EN, Bozza PT, Pessolani MC. Modulation of lipid droplets by Mycobacterium leprae in Schwann cells: a putative mechanism for host lipid acquisition and bacterial survival in phagosomes. Cell Microbiol. 2011 Feb;13(2):259-273.

<>Melo RC, D'Avila H, Wan HC, Bozza PT, Dvorak AM, Weller PF. Lipid bodies in inflammatory cells: structure, function, and current imaging techniques. JHistochem Cytochem. 2011 May;59(5):540-56.

<http://dx.doi.org/10.1016/j.lfs.2011.03.001 | _blank >> Salluh JI, Soares M, Coelho LM, Bozza FA, Verdeal JC, Castro-Faria-Neto HC, e Silva JR, Bozza PT, Póvoa P. Impact of systemic corticosteroids on the clinical course and outcomes of patients with severe community-acquired pneumonia: A cohort study cohort study. J Crit Care. 2011 Apr;26(2):193-

<> Pinto Júnior VLL, Rebelo MC, Gomes RN, de Assis EF, Castro-Faria Neto HC, Bóia MN. IL-6 and IL-8 in cerebrospinal fluid from patients with aseptic meningitis and bacterial meningitis: their potential role as a marker for differential diagnosis. Braz J Infect Dis. 2011;15(2):156-158.

2010

Salluh JI, Bozza FA, Japiassu AM, Faria Neto HC, Bozza PT, Povoa P 2010. Corticosteroids in sepsis: Pathophysiological rationale and the selection of patients. Endocr. Metab. Immune Disord Drug Targets 10: 266-273.

Lachtermacher S, Esporcatte BL, Montalvão F, Costa PC, Rodrigues DC, Belem L, Rabischoffisky A, Faria Neto HC, Vasconcellos R, Iacobas S, Iacobas DA, Dohmann HF, Spray DC, Goldenberg RC, Campos-de-Carvalho AC 2010. Cardiac gene expression and systemic cytokine profile are complementary in a murine model of post-ischemic heart failure. Braz J Med Biol Res 43: 377-389.

Guerra CS, Silva RM, Carvalho LO, Calabrese KS, Bozza PT, Côrte-Real S 2010. Histopathological analysis of initial cellular response in TLR-2 deficient mice experimentally infected by Leishmania (L.) amazonensis. Int J Exp Pathol 91: 451-459.

Mafra de Lima F, Villaverde AB, Salgado MA, Castro-Faria-Neto HC, Munin E, Albertini R, Aimbire F 2010. Low intensity laser therapy (LILT) in vivo acts on the neutrophils recruitment and chemokines/cytokines levels in a model of acute pulmonary inflammation induced by aerosol of lipopolysaccharide from Escherichia coli in rat. J Photochem Photobiol B 101: 271-278.

Salluh JI, Shinotsuka CR, Soares M, Bozza FA, Lapa e Silva JR, Tura BR, Bozza PT, Vidal CG 2010. Cortisol levels and adrenal response in severe community-acquired pneumonia: a systematic review of the literature. J Crit Care 25: 541.e1-541.e8.

Chao MC, Garcia CS, de Oliveira MB, Santos RS, Lucas IH, Silva PL, Vieira-Abreu A, de Castro-Faria-Neto HC, Parra-Cuentas ER, Capelozzi VL, Pelosi P, Rocco PR 2010. Degree of endothelium injury promotes fibroelastogenesis in experimental acute lung injury. Respir Physiol Neurobiol 173: 179-188.

Bozza FA, Carnevale R, Japiassá AM, Castro-Faria-Neto HC, Angus DC, Salluh JI 2010. Early fluid resuscitation in sepsis: evidence and perspectives. Shock 34 suppl 1: 40-43.

Bozza PT, Viola JP 2010. Lipid droplets in inflammation and cancer. Prostaglandins Leukot Essent Fatty Acids 82: 243-250.

Gimenez G, Magalhães KG, Belaunzarán ML, Poncini CV, Lammel EM, Gonzalez Cappa SM, Bozza PT, Isola EL 2010. Lipids from attenuated and virulent Babesia bovis strains induce differential TLR2-mediated macrophage activation. Mol Immunol 47: 747-755.

Zimmerman GA, Castro-Faria-Neto HC 2010. Persistent cognitive impairment after cerebral malaria: models, mechanisms and adjunctive therapies. Expert Rev Anti Infect Ther 8: 1209-1212.

Bozaquel-Morais BL, Madeira JB, Maya-Monteiro CM, Masuda CA, Montero-Lomeli M 2010. A new fluorescence-based method identifies protein phosphatases regulating lipid droplet metabolism. PLoS One 5.

Araújo IM, Abreu SC, Maron-Gutierrez T, Cruz F, Fujisakl L, Carreira H Jr, Ornellas F, Ornellas D, Vieira-de-Abreu A, Castro-Faria-Neto HC, Muxfeldt Ab´Saber A, Teodoro WR, Diaz BL, Peres da Costa C, Capelozzi VL, Pelosi P, Morales MM, Rocco PR 2010. Bone marrow-derived mononuclear cell therapy in experimental pulmonary and extrapulmonary acute lung injury. Crit Care Med 38: 1733-1741.

Reis PA, Comim CM, Hermani F, Silva B, Barichello T, Portella AC, Gomes FC, Sab IM, Frutuoso VS, Oliveira MF, Bozza PT, Bozza FA, Dal-Pizzol F, Zimmerman GA, Quevedo J, Castro-Faria-Neto HC 2010. Cognitive dysfunction is sustained after rescue therapy in experimental cerebral malaria, and is reduced by additive antioxidant therapy. PLoS Pathog 6.

Assunção-Miranda I, Amaral FA, Bozza FA, Fagundes CT, Sousa LP, Souza DG, Pacheco P, Barbosa-Lima G, Gomes RN, Bozza PT, da Poian AT, Bozza MT 2010. Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection. FASEB J 24: 218-228.

Paiva LA, Maya-Monteiro CM, Bandeira-Melo C, Silva PM, El-Cheikh MC, Teodoro AJ, Borojevic R, Perez SA, Bozza PT 2010. Interplay of cysteinyl leukotrienes and TGF-beta in the activation of hepatic stellate cells from Schistosoma mansoni granulomas. Biochim Biophys Acta 1801: 1341-1348.

Mattos KA, Rodrigues LS, Oliveira VG, Sarno EN, Atella GC, Pereira GM, Bozza PT, Pessolani MC 2010. Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis. J Leukoc Biol 87: 371-384.

Araújo-Santos T, Prates DB, Andrade BB, Nascimento DO, Clarêncio J, Entringer PF, Carneiro AB, Silva-Neto MA, Miranda JC, Brodskyn CI, Barral A, Bozza PT, Borges VM 2010. Lutzomyia longipalpis saliva triggers lipid body formation and prostaglandin E2 production in murine macrophages. PLoS Negl Trop Dis 4.

Amarante-Mendes GP, Bortoluci KR, Bozza PT, Chammas R, Viola JP 2010. Paradise revealed: first-class science rocked by the sound of the waves. Cell Death Differ 17: 1368-1372.

Magalhães KG, Almeida PE, Atella GC, Maya-Monteiro CM, Castro-Faria-Neto HC, Pelajo-Machado M, Lenzi H, Bozza MT, Bozza PT 2010. Schistosomal-derived lysophosphatidylcholine are involved in eosinophil activation and recruitment through toll-like receptor-2-dependent mechanisms. J Infect Dis 202: 1369-1379.

Bozza FA, Garteiser P, Oliveira MF, Doblas S, Cranford R, Saunders D, Jones I, Towner RA, Castro-Faria-Neto HC 2010. Sepsis-associated encephalopathy: a magnetic resonance imaging and spectroscopy study. J Cereb Blood Flow Metab 30: 440-448.

2009

<> Bozza P. T, D Avila H, Almeida P. E, Magalhães K. G, Molinaro R, Almeida C. J, Maya-Monteiro C. M. Lipid droplets in host pathogen interactions. Clinical Lipidology. 2009 Dec; 4(6): 791-807.

<> Gomes M.B, Cobas R.A, Nunes E, Castro-Faria-Neto H.C, da Matta M.F, Neves R, Tibiriçá E. Plasma PAF-acetylhydrolase activity, inflammatory markers and susceptibility of LDL to in vitro oxidation in patients with type 1 diabetes mellitus. Diabetes research and clinical practice. 2009 Jul; 85(1):61-68.

<> Japiassú M.A,  Salluh J.I.F, Bozza P.T, Bozza F.A, Castro-Faria-Neto H.C. Revisiting steroid treatment for septic shock: molecular actions and clinical effects - a review. Memórias do Instituto Oswaldo Cruz. 2009 jul; 104(4): 531-548.

<> Medeiros M.N, Belmonte R, Soares B. C, Medeiros L. N, Canetti C, Freire-De-Lima C. G, Monteiro C. M. M, Bozza P. T, Almeida I. C, Masuda H, Kurtenbach E, Machado E.A. Arrest of oogenesis in the bug Rhodnius prolixus challenged with the fungus Aspergillus niger is mediated by immune response-derived PGE(2). Journal of Insect Physiology.2009 Fev; 55(2):150-157.

<> Pinheiro RO, Nunes MP, Pinheiro CS, D'Avila H, Bozza PT, Takiya CM, Côrte-Real S, Freire-de-Lima CG, DosReis GA, Induction of autophagy correlates with increased parasite load of Leishmania amazonensis in BALB/c but not C57BL/6 macrophages, 2009, Microbes and Infection, volume 11, Issue 2, pages 181-90. 

<>  Moreira L. S, Piva B, Gentile L. B, Mesquita-Santos F. P, Davila H, Maya-Monteiro C.M, Bozza P. T, Bandeira-Melo C, Diaz B. L. Cytosolic phospholipase A-2driven PGE2 synthesis within unsaturated fatty acids-induced lipid bodies of epithelial cells. Biochimica et Biophysica Acta- Molecular and Cell Biology of Lipids.2009 Mar; 1791(3):156-165.

<>  Samsa M.M, Mondotte J. A, Iglesias N. G, Assunção-Miranda I, Barbosa-Lima G, Da Poian A. T, Bozza P. T, Gamarnik A. V. Dengue virus capsid protein usurps lipid droplets for viral particle formation. PLoS Pathogens.2009 out; 5(10): 1000632.

<>  Silva P. L, Garcia C. S, Maronas P. A, Cagido V. R, Negri  E. M, Damaceno-Rodrigues N. R, Ventura G. M, Bozza P. T, Zin W. A, Capelozzi V. L, Pelosi P, Rocco P. R. M. Early short-term versus prolonged low-dose methylprednisolone therapy in acute lung injury. The European Respiratory Journal. 2009 Mar; 33(3): 634-645.

<>  Sorgi C. A, Secatto A, Fontanari C, Turato W. M, Belanger  C, Medeiros A. I, Kashima S, Marleau S, Covas D. T, Bozza P. T, Faccioli L. H. Histoplasma capsulatum Cell Wall {beta}-Glucan Induces Lipid Body Formation through CD18, TLR2, and Dectin-1 Receptors: Correlation with Leukotriene B4 Generation and Role in HIV-1 Infection. Journal of Immunology .2009; 182: 4025-4035.

<> Oliveira G. P, Oliveira M. B. G, Santos R. S, Lima L. D, Dias C. M, Teodoro W. R, Capelozzi V. L, Gomes R. N, Bozza P. T, Pelosi P, Rocco P. R. M. Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis. Critical Care. 2009 May; 13:R74.

<> Bozza P. T, Magalhaes K. G, Weller P. F. Leukocyte lipid bodies - Biogenesis and functions in inflammation. BBA. Molecular and Cell Biology of Lipids. 2009 Jun;  1791(6): 540-551.

<> Silva A. R, Pacheco P, Vieira-De-Abreu A, Maya-Monteiro C.M, D'Alegria B, MAGALHAES K. G, Assis E. F, Bandeira-Melo C, Castro- Faria-Neto H.C, Bozza P. T. Lipid bodies in oxidized LDL-induced foam cells are leukotriene-synthesizing organelles: a MCP-1/CCL2 regulated phenomenon. BBA. Molecular and Cell Biology of Lipids. 2009 Nov; 1791(11): 1066-1075.

<> Magalhães E. S, Paiva C. N, Pyrrho A. S, Mourão-Sá D, Amâncio R. T, Figueiredo R. T, Vieira-De-Abreu  A, Dutra H. S, Silveira M. S, Gaspar-Elsas M. I, Bozza P. T, Bozza M. Macrophage migration inhibitory factor is critical to interleukin-5-driven eosinophilopoiesis and tissue eosinophilia triggered by Schistosoma mansoni infection. The FASEB Journal. 2009; 23: 1262-1271.

<> Almeida P.E, Silva A.R, Maya-Monteiro C.M, Töröcsik D, D'Avila H, Dezsö B, Magalhães KG, Castro-Faria-Neto H. C, Nagy L, Bozza P.T. Mycobacterium bovis bacillus Calmette-Guérin infection induces TLR2-dependent peroxisome proliferator-activated receptor gamma expression and activation: functions in inflammation, lipid metabolism, and pathogenesis. The journal of immunology. 2009 Jul; 183(2):1337-1345.

<> Albuquerque L.M, Trugilho M.R.O, Chapeaurouge A, Jurgilas P.B, Bozza P.T, Bozza F.A, Perales J, Neves-Ferreira A. G. C. Two-Dimensional Difference Gel Electrophoresis (DiGE) Analysis of Plasmas from Dengue Fever Patients. Journal of Proteome Research. 2009 Dec;8(12):5431-5441.

2008

Gomes MD, Cobas RA, Nunes E, Nery M, Faria Neto HCC, Tibiriçá EV 2008. Serum platelet-activating factor acetylhydrolase activity: A novel potential inflammatory marker in type 1 diabetes. Prostag Oth Lipid M 87: 42-46.

Salluh JIF, Bozza FA, Soares M, Verdeal JCR, Faria Neto HCC, Silva JRLE, Bozza PT 2008. Adrenal response in severe community-acquired pneumonia: Impact on outcomes and disease severity. Chest 134: 947-954.

Salluh J.I.F, Bozza PT 2008. Biomarkers of sepsis: Lost in translation?. Crit Care Med 36: 2192-2194.

Miyazaki Y, Bunting M, Stafforini DM, Mcintyre TM, Prescott SM, Frutuoso VS, Amendoeira FC, Nascimento DO, Abreu AV, Faria Neto HCC, Zimmerman G 2008. Integrin alphaDbeta2 is dynamically expressed by inflamed macrophages and alters the natural history of lethal systemic infections. J Immunol 180: 590-600.

Monteiro CMM, Almeida PE, Martins AS, Rezende AP, Faria Neto HCC, Bozza PT 2008. Leptin induces macrophage lipid body formation by a phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent mechanism. J Biol Chem 283: 2203-2210.

Accioly MT, Pacheco P, Monteiro CMM, Carrossini N, Robbs BK, Oliveira SS, Kaufmann C, Morgado-Diaz J A, Bozza PT, Viola JP 2008. Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells. Cancer Res 68: 1732-1740.

Leite-junior, JHP, Garcia CS, Souza-fernandes AB, Silva PL, Ornellas DS, Larangeira, AP, Faria Neto HCC, Morales MM, Negri, EM, Capelozzi VL, Zin WA, Pelosi P, Bozza PT, Rocco PR 2008. Methylprednisolone improves lung mechanics and reduces the inflammatory response in pulmonary but not in extrapulmonary mild acute lung injury in mice. Crit Care Med 36: 2621-2628.

Roque NR, Cardoso RM, Faria Neto HCC, Melo RCN, Bozza PT 2008. Neutrophils recruited to the site of Mycobacterium bovis BCG infection undergo apoptosis and modulate lipid body biogenesis and prostaglandin E2 production by macrophages. Cell Microbiol 10: 2589-2604.

Salluh J, Soares M 2008. New recommendations for the use of corticosteroids in sepsis: not so fast!. Crit Care Med 36: 2489-2490.

Monteiro CMM, Bozza PT 2008. Leptin and mTOR: Partners in metabolism and inflammation. Cell Cycle 7: 1713-1717.

Monteiro CMM, Bozza PT 2008. Lipid bodies in innate immune response to bacterial and parasite infections. Int Immunopharmacol 8: 1308-1315.

Plotkowski MC, Brandão BA, Assis MC, Feliciano LF, Raymond B, Freitas C, Saliba AM, Zahm JM, Touqui L, Bozza PT 2008. Lipid body mobilization in the ExoU-induced release of inflammatory mediators by airway epithelial cells. Microb Pathogenesis 45: 30-37.

Aimbire F, Santos FV, Albertini R, Faria Neto HCC, Pacheco-Soares C 2008. Low-level laser therapy decreases levels of lung neutrophils anti-apoptotic factors by a NF-kappaB dependent mechanism. Int Immunopharmacol 8: 603-605.

Bozza FA, Cruz OG, Zagne SM, Nogueira RM, Assis EF, Bozza PT, Kubelka CF 2008. Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity. BMC Infect Dis 8.

Salluh JI, Bozza PT, Bozza FA 2008. Surviving sepsis campaign: a critical reappraisal. Shock 30 Suppl 1: 70-72.

Salluh JI, Povoa P, Soares M, Faria Neto HCC, Bozza FA, Bozza PT 2008. The role of corticosteroids in severe community-acquired pneumonia: a systematic review. Crit Care 12.

2007

De Castro SH, Faria Neto HCC, Gomes MB 2007. Platelet-activating factor acetylhydrolase (PAF-AH)activity in patients with type 1 diabetes mellitus. Arq Bras Cardiol 88: 179-184.

Frutuoso VS, Magalhães MM, Amendoeira FC, Almeida ALF, Nascimento DD, Berenger AL, Kaplan MA, Ma K, Bozza PT, Faria Neto HCC 2007. Analgesic and anti-inflammatory activity of the aqueous extract of Rheedia longifolia Planch & Triana. . Mem Inst Oswaldo Cruz 102: 91-96.

Aimbire F, Lopes-Martins RA, Albertini R, Pacheco MT, Faria Neto HCC, Martins PMRS 2007. Effect of low-level laser therapy on hemorrhagic lesions induced by immune complex in rat lungs. Photomed Laser Surg 77: 112-117.

Bozza FA, Salluh JI, Soares M, M S, Gomes RN, Bozza MT, Faria Neto HCC, Bozza PT 2007. Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis. Crit Care 11.

Vasquez-Pinto LM, Landgraf RG, Bozza PT, Jancar S 2007. High vascular endothelial growth factor levels in NZW mice do not correlate with collagen deposition in allergic asthma. Int Arch Allergy Immunol 142: 19-27.

Salluh J, Silva AR, Gomes RN, Souza HS, Jandre FC, Giannella-Neto A, Zimmerman GA, Zimmerman GA, Faria Neto HCC, Bozza PT 2007. Lung production of platelet-activating factor acetylhydrolase in oleic acid-induced acute lung injury. Prostaglandins Leukot Essent Fatty Acids 77: 1-8.

Carvalho AR, Jandre FC, Pino AV, Bozza FA, Bozza FA, Rodrigues R, Ascoli FO, Giannella-Neto A 2007. Positive end-expiratory pressure at minimal respiratory elastance represents the best compromise between mechanical stress and lung aeration in oleic acid induced lung injury. Crit Care 11.

Vieira RP, Claudino RC, Duarte AC, Santos AB, Perini A, Faria Neto HCC, Mauad T, Martins MA, Dolhnikoff M, Carvalho CR 2007. Aerobic exercise decreases chronic allergic lung inflammation and airway remodeling in mice. Am J Respir Crit Care Med 176: 871-877.

Bozza PT, Melo RC, Bandeira-de-Melo C 2007. Leukocyte lipid bodies regulation and function: contribution to allergy and host defense.. Pharmacol Therapeut 113: 30-49.

Magalhães ES, Mourão-Sa DS, Abreu AV, Figueiredo RT, Pires ALA, Viola JP, Martins MA, Faria Neto HCC, Bozza PT, Bozza MT 2007. Macrophage migration inhibitory factor is essential for allergic asthma but not for Th2 differentiation. Eur J Immunol 37: 1097-1106.

Pacheco P, Abreu AV, Gomes RN, Lima GB, Monteiro CMM, Silva AR, Bozza PT 2007. Monocyte chemoattractant protein-1/CC chemokine ligand 2 controls microtubule-driven biogenesis and leukotriene B4-synthesizing function of macrophage lipid bodies elicited by innate immune response. J Immunol 15: 8500-8508.

Almeida PE, Roque NR, Faria Neto HCC, Bozza PT 2007. Toll-like receptor-2-mediated C-C chemokine receptor 3 and eotaxin-driven eosinophil influx induced by Mycobacterium bovis BCG pleurisy. Infect Immun 75: 1507-1511.

2006

Pitombo MB, Lupi OH, Gomes RN, Amancio R, Refinetti RA, Bozza PT, Castro-Faria-Neto HC 2006. Inflammatory response and bacterial dissemination after laparotomy and abdominal CO2 insufflation in a murine model of peritonitis. Surg Endosc 20: 1440-1447.

Aimbire F, Lopes-Martins RA, Castro-Faria-Neto HC, Albertini R, Chavantes MC, Pacheco MT, Leonardo PS, Iversen VV, Bjordal JM 2006. Low-level laser therapy can reduce lipopolysaccharide-induced contractile force dysfunction and TNF-alpha levels in rat diaphragm muscle. Laser Med Sci 21: 238-244.

Aimbire F, Albertini R, Pacheco MT, Castro-Faria-Neto HC, Leonardo PS, Iversen VV, Lopes-Martins RA, Bjordal JM 2006. Low-level laser therapy induces dose-dependent reduction of TNFalpha levels in acute inflammation. Photomed Laser Surg 24: 33-37.

Graça-Souza AV, Maya-Monteiro C, Paiva-Silva GO, Braz GR, Paes MC, Sorgine MH, Oliveira MF, Oliveira PL 2006. Adaptations against heme toxicity in blood-feeding arthropods.. Insect Biochem Mol Biol 36: 322-335.

Bezerra-Santos CR, Vieira-de-Abreu A, Barbosa-Filho JM, Bandeira-Melo C, Piuvezam MR, Bozza PT 2006. Anti-allergic properties of Cissampelos sympodialis and its isolated alkaloid warifteine. Int Immunopharmacol 6: 1152-1160.

de-Mendonça-Filho HT, Pereira KC, Fontes M, Vieira DA, de-Mendonça ML, Campos LA, Castro-Faria-Neto HC 2006. Circulating inflammatory mediators and organ dysfunction after cardiovascular surgery with cardiopulmonary bypass: a prospective observational study. Crit Care 10: 46-46.

Gomes RN, Bozza FA, Amâncio RT , Japiassú AM, Vianna RC, Larangeira AP, Gouvea JM, Bastos MS, Zimmerman GA, Satfforini DM, Prescott SM, Bozza PT, Castro-Faria-Neto HC 2006. Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis. Shock 26: 41-49.

Vasques E, Almeida AL, Noya V, D Alegria B, Marathe G, McIntyre TM, Tibiriça E, Bozza PT, Silva AR, Castro-Faria-Neto HC 2006. Impairment of endothelium-dependent aorta relaxation by phospholipid components of oxidized low-density lipoprotein.. Endothelium J Endoth 13: 1-8.

Gomes RN, Figueiredo RT, Bozza FA, Pacheco P, Amancio RT, Laranjeira AP, Castro-Faria-Neto HC, Bozza PT, Bozza MT 2006. Increased susceptibility to septic and endotoxic shock in monocyte chemoattractant protein 1/cc chemokine ligand 2-deficient mice correlates with reduced interleukin 10 and enhanced macrophage migration inhibitory factor production. Shock 26: 457-463.

Lima RG, Moreira L, Paes-Leme J, Barreto-de-Souza V, Castro-Faria-Neto HC, Bozza PT, Bou-Habib DC 2006. Interaction of macrophages with apoptotic cells enhances HIV Type 1 replication through PGE2, PAF, and vitronectin receptor. AIDS Res Hum Retroviruses 22: 763-769.

Aimbire F, Bjordal JM, Iversen VV, Albertini R, Frigo L, Pacheco MT, Castro-Faria-Neto HC, Chavantes MC, Labat RM, Lopes-Martins RA 2006. Low level laser therapy partially restores trachea muscle relaxation response in rats with tumor necrosis factor alpha-mediated smooth airway muscle dysfunction. Laser Surg Med 38: 773-778.

Paiva-Silva GO, Cruz-Oliveira C, Nakayasu ES, Maya-Monteiro CM, Dunkov BC, Masuda H, Almeida IC, Oliveira PL 2006. A heme-degradation pathway in a blood-sucking insect.. Proc Natl Acad Sci USA 103: 8030-8035.

Mesquita-Santos FP, Vieira-de-Abreu A, Calheiros AS, Figueiredo IH, Castro-Faria-Neto HC, Weller PF, Bozza PT, Diaz BL, Bandeira-Melo C 2006. Cutting edge: prostaglandin D2 enhances leukotriene C4 synthesis by eosinophils during allergic inflammation: synergistic in vivo role of endogenous eotaxin.. J Immunol 176: 1326-1330.

Barreto-de-Souza V, Pacheco GJ, Silva AR, Castro-Faria-Neto HC, Bozza PT, Saraiva EM, Habib DC 2006. Increased Leishmania replication in HIV-1-infected macrophages is mediated by tat protein through cyclooxygenase-2 expression and prostaglandin E2 synthesis. J Infect Dis 194: 846-854.

DAvila H, Melo RC, Parreira GG, Werneck-Barroso E, Castro-Faria-Neto HC, Bozza PT 2006. Mycobacterium bovis bacillus Calmette-Guerin induces TLR2-mediated formation of lipid bodies: intracellular domains for eicosanoid synthesis in vivo. J Immunol 176: 3087-3097.


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