ARTIGOS CIENTÍFICOS
Confira a lista dos artigos publicados em periódicos indexados pelos pesquisadores do Laboratório de Genômica Funcional e Bioinformática do Instituto Oswaldo Cruz (IOC/Fiocruz):
2014
Indexado (fator de impacto < 1 ou sem FI)
Sa, RA, Moreira AS, Cabello PH, Ornelas, AA, Costa, EB, Matos, CS, Alves, G, Hatagima, A 2014. Human glutathione S-transferase polymorphisms associated with prostate cancer in the Brazilian population.. Int Braz J Urol 40: 463-473.Ponce de Leon, M., Miranda AB, Alvarez-Valin, F., Carels N 2014. The Purine Bias of Coding Sequences is Determined by Physicochemical Constraints on Proteins. Bioinform Biol Insights 8: 93-108.
Indexado (fator de impacto >=1 e < 2,71)
Oliveira, SD, Nanini, HF, Savio, LE, Waghabi MC, Silva, CL, Coutinho-Silva, R 2014. Macrophage P2X7 receptor function is reduced during schistosomiasis: putative role of TGF- β1. Mediat Inflamm 2014: - .Indexado (fator de impacto >=2,71 e < 4,35)
Galvão TC, Cristiane Rodrigues Lima, Gomes LHF, Talita Duarte Pagani, Alves-Ferreira M, Gonçalves AJS, Corrêa PR, Degrave WM, Mendonça-Lima L 2014. The BCG Moreau RD16 deletion inactivates a repressor reshaping transcription of an adjacent gene. Tuberculosis 94: 26-33.Qualis B2
Degrave WM 2014. A importância do sequenciamento do genoma de Mycobacterium tuberculosis, um marco na pesquisa da Tuberculose.. Ciência Hoje 319: 54-56.
2013
Indexado (fator de impacto < 1 ou sem FI)
Carels N, Frias D 2013. A Statistical Method without Training Step for the Classification of Coding Frame in Transcriptome Sequences. Bioinform Biol Insights 7: 35-54.
Indexado (fator de impacto >=1 e < 2,71)
Saraiva, RM, Waghabi MC, Vilela, MF, Madeira, FS, da Silva, GM, Xavier, SS, Feige, JJ, Hasslocher-Moreno, AM, Araujo-Jorge TC 2013. Predictive value of transforming growth factor-â1in Chagas disease: towards a biomarker surrogate of clinical outcome. T Roy Soc Trop Med H 107: 518-525.
Victalina-de-Almeida D, Morgado MG, Côrtes FH, Guimaraes ML, Mendonça-Lima L, Pilotto JH, Beatriz Grinsztejn, Valdilea Goncalves Veloso, Bongertz V 2013. Short communication: neutralizing antibodies in HIV-1-infected Brazilian individuals.. AIDS Res Hum Retrov 29: 488-492.
Indexado (fator de impacto >=2,71 e < 4,35)
Santos LO, A. S. Garcia-Gomes, Catanho M, Sodre CL, Santos AL, Branquinha MH,, d Avila-Levy CM 2013. Aspartic Peptidases of Human Pathogenic Trypanosomatids: Perspectives and Trends for Chemotherapy. Curr Med Chem 20: 3116-3133.
Fares, RC, Gomes, JA, Garzoni LR, Waghabi MC, Saraiva, RM, Medeiros, NI, Oliveira-Prado, R, Sangenis, LH, Chambela, MC, de Araujo, FF, Teixeira- Carvalho, A, Damasio, MP, Valente, VA, Ferreira, KS, Souza, GR, Rocha, MO, Correa-Oliveira, R 2013. Matrix metalloproteinases 2 and 9 are differentially expressed in patients with indeterminate and cardiac clinical forms of Chagas disease. Infect Immun 81(10): 3600-3608.
Jun Han, Luis Caetano Antunes, Jingxi Pan, Moreira CJC, Azambuja P, Christoph H Borchers, Carels N 2013. Metabolic Signatures of Triatomine Vectors of Trypanosoma cruzi Unveiled by Metabolomics. PLoS One 8: - .
Indexado (fator de impacto >=4,35 e < 7,51)
Rodrigues CM, Menna-Barreto RFS, Sabois-Vahia, R, da Silva, SA, Souza EM, Waghabi MC, Cuervo P, de Jesus, JB 2013. Cellular growth and mitochondrial ultrastructure of leishmania (Viannia) braziliensis promastigotes are affected by the iron chelator 2,2-dipyridyl. PLoS Neglect Trop D 7(10): - .
2012
Indexado (fator de impacto < 1 ou sem FI)
Lifschitz S, Viana CJ, Ttristão C, Catanho M, Degrave W, Miranda AB, Bezerra M, Otto TD 2012. Design and implementation of ProteinWorldDB. Lect Notes Comput Sci 7409: 144-155.
Indexado (fator de impacto >=1 e < 2,71)
Lacerda DI, Cysne-Finkelstein L, Nunes MP, De-Luca PM, Genestra MS, Leon LL, Berrêdo-Pinho M, Mendonça-Lima L, Matos DC, Medeiros MA, Mendonça SC 2012. Kinetoplastid membrane protein-11 exacerbates infection with Leishmania amazonensis in murine macrophages. Mem Inst Oswaldo Cruz 107: 238-245.
Indexado (fator de impacto >=2,71 e < 4,35)
Ferrão PM, de Oliveira FL, Degrave WM, Araujo-Jorge TC, Mendonça-Lima L, Waghabi MC 2012. A phosphoproteomic approach towards the understanding of the role of TGF-beta in Trypanosoma cruzi biology. PLoS One 7: - .
Indexado (fator de impacto >=4,35 e < 7,51)
da Mota FF, Marinho LP, Moreira CJ, Lima MM, Mello CB, Garcia ES, Carels N, Azambuja P 2012. Cultivation-independent methods reveal differences among bacterial gut microbiota in triatomine vectors of Chagas disease. PLoS Negl Trop Dis 6: - .
de Oliveira FL, Araujo-Jorge TC, de Souza EM, de Oliveira GM, Degrave WM, Feige JJ, Bailly S, Waghabi MC 2012. Oral administration of GW788388, an inhibitor of transforming growth factor beta signaling, prevents heart fibrosis in Chagas disease. PLoS Negl Trop Dis 6: -
Araujo-Jorge TC, Waghabi MC, Bailly S, Feige JJ 2012. The TGF-β pathway as an emerging target for Chagas disease therapy. Clin Pharmacol Ther 92: 613-621.
2011
<> Berrêdo-Pinho M, Kalume DE, Correa PR, Gomes LH, Pereira MP, da Silva RF, Castello-Branco LR, Degrave WM, Mendonça-Lima L. Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur. BMC Microbiol. 2011 Apr 20;11:80
<> Gomes AF, Guimarães EV, Carvalho L, Correa JR, Mendonça-Lima L, Barbosa HS. Toxoplasma gondii down modulates cadherin expression in skeletal muscle cells inhibiting myogenesis. BMC Microbiol. 2011 May 18;11:110.
<> Otto TD, Dillon GP, Degrave WS, Berriman M. RATT: Rapid Annotation Transfer Tool. Nucleic Acids Res. 2011 May;39(9):e57.
<> Silva MR, Guimarães MD, Oliveira VM, Moreira A dos S, Costa RR, Abi-Zaid KC, Rocha A da S, Suffys PN. Identification of Mycobacterium tuberculosis complex based on amplification and sequencing of the oxyR pseudogene from stored Ziehl-Neelsen-stained sputum smears in Brazil. Mem Inst Oswaldo Cruz. 2011 Feb;106:9-15.
2010
Monnerat LS, Moreira AS, Alves MC, Bonvicino CR, Vargas FR 2010. Identification and characterization of novel sequence variations in MECP2 gene in Rett syndrome patients. Brain Dev 32: 843-848.
Braggio E, Braggio DA, Small IA, Lopes LF, Valadão M, Gouveia ME, Moreira AS, Linhares E, Romano S, Bacchi CE, Renault IZ, Guimarães DP, Ferreira CG 2010. Prognostic relevance of KIT and PDGFRA mutations in gastrointestinal stromal tumors. Anticancer Res 30: 2407-2414.
Romanha AJ, Castro SL, Soeiro MN, Lannes-Vieira J, Ribeiro I, Talvani A, Bourdin B, Blum B, Olivieri B, Zani C, Spadafora C, Chiari E, Chatelain E, Chaves G, Calzada JE, Bustamante JM, Freitas-Junior LH, Romero LI, Bahia MT, Lotrowska M, Soares M, Andrade SG, Armstrong T, Degrave W, Andrade Zde A 2010. In vitro and in vivo experimental models for drug screening and development for Chagas disease. Mem Inst Oswaldo Cruz 105: 233-238.
Teixeira RL, Silva Jr FP, Silveira AR, Cabello PH, Mendonça-Lima L, Rabahi MF, Kritski AL, Mello FC, Suffys PN, de Miranda AB, Santos AR 2010. Sequence analysis of NAT2 gene in Brazilians: Identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure. MUTAT RES-FUND MOL M 683: 43-49.
Capriles PV, Guimarães AC, Otto TD, Miranda AB, Dardenne LE, Degrave WM 2010. Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for Chagas disease treatment. BMC Genomics 11.
Teles RM, Teles RB, Amadeu TP, Moura DF, Mendonça-Lima L, Ferreira H, Santos IM, Nery JA, Sarno EN, Sampaio EP 2010. High matrix metalloproteinase production correlates with immune activation and leukocyte migration in leprosy reactional lesions. Infect Immun 78: 1012-1021.
Otto TD, Catanho M, Tristão C, Bezerra M, Fernandes RM, Elias GS, Scaglia AC, Bovermann B, Berstis V, Lifschitz S, de Miranda AB, Degrave WM 2010. ProteinWorldDB: querying radical pairwise alignments among protein sets from complete genomes. Bioinformatics 26: 705-707.
2009
<>Carels N, Frías D, Classifying coding DNA with nucleotide statistics, 2009, Bioinformatics & Biology Insights, Volume 28, Issue 3, Pages 141-54.
<> Cuervo P, de Jesus JB, Saboia-Vahia L, Mendonça-Lima L, Domont GB, Cupolillo E, Proteomic characterization of the released/secreted proteins of Leishmania (Viannia) braziliensis promastigotes, 2009, Journal of Proteomics, Volume 2;73, Issue 1, Pages 79-92.
<>Carels N, Vidal R. Frías D, Universal features for the classification of coding and non-coding DNA sequences, 2009, Bioinformatics & Biology Insights (online) Volume 3, Issue 3, Pages 37-49.
<http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000800006&lng=en&nrm=iso&tlng=en _blank>> Alves-Ferreira M, Guimarăes A, Capriles P, Dardenne L, Degrave W. A new approach for potential drug target discovery through in silico metabolic pathway analysis using Trypanosoma cruzi genome information. Mem Inst Oswaldo Cruz. 2009 Dec;104(8):1100-10.
<http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000800004&lng=en&nrm=iso&tlng=en | _blank>> Waghabi MC, Coutinho-Silva R, Feige JJ, Higuchi MD, Becker D, Burnstock G, et al. Gap junction reduction in cardiomyocytes following transforming growth factor- beta treatment and Trypanosoma cruzi infection. Memorias Do Instituto Oswaldo Cruz. 2009 Dec;104(8):1083-90.
<http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000800001&lng=en&nrm=iso&tlng=en | _blank>> Coutinho L, Ferreira MA, Cosson A, Batista MM, Batista DDJ, Minoprio P, et al. Inhibition of Trypanosoma cruzi proline racemase affects host-parasite interactions and the outcome of in vitro infection. Memorias Do Instituto Oswaldo Cruz. 2009 Dec;104(8):1055-62.
Sodré C, Chapeaurouge A, Kalume D, de Mendonça Lima L, Perales J, Fernandes O. Proteomic map of Trypanosoma cruzi CL Brener: the reference strain of the genome project. Arch Microbiol. 2009 Feb;191(2):177-84. Arch Microbiol
<> Wanieck PJ, Mendonça-Lima L, Menezes GB, Jansen AM, Araújo CAC, Recombinant expression and characterization of a lysozyme from the midgut of Triatoma brasiliensis (Hemiptera, Reduviidae) in comparison with intestinal muramidase activity, 2009, Physiological Entomology, Volume 34, Issue 4, Pages 309-317.
<> Carvalho PC, Fischer JS, Chen EI, Domont GB, Carvalho MG, Degrave WM, Yates JR, Barbosa VC, GO Explorer: A gene-ontology tool to aid in the interpretation of shotgun proteomics data, 2009, Proteome Science, Volume 24, Issue 7, Page 6.
<> Carvalho V. F, Barreto E.O, Farias-Filho F.A, Gomes L.H, Mendonça L. L, Cordeiro R.S, Martins M.A, Rodrigues e Silva P.M. Reduced expression of IL-3 mediates intestinal mast cell depletion in diabetic rats: role of insulin and glucocorticoid hormones. International Journal of Experimental Pathology. 2009 Apr; 90(2):148-155.
<> Waghabi MC, de Souza EM, de Oliveira GM, Keramidas M, Feige JJ, Araujo-Jorge TC, et al. Pharmacological Inhibition of Transforming Growth Factor beta Signaling Decreases Infection and Prevents Heart Damage in Acute Chagas' Disease. Antimicrobial Agents and Chemotherapy. 2009 Nov;53(11):4694-701.
Laboratório de Hanseníase - LAHAN
<> Slim FJ, Illarramendi X, Maas M, Sampaio EP, Nery JAC, Sarno EN, Faber WR. The Potential Role of Magnetic Resonance Imaging in Patients with Hansen’s Neuropathy of the Feet: A Preliminary Communication. International Journal of Lower Extremity Wounds. 2009;8:169-173.
<> Jardim MR, Vital R, Illarramendi X, Antunes SLG, Nery JAC, Sales AM, Ulnar Neuropathy As A First Sign Of Hiv Infection A diagnostic challenge for leprosy endemic countries, 2009, Arquivos De Neuro-Psiquiatria, volume 67, Issue 3A, pages 726-9.
Fontes ANB, Sakamuri RM, Baptista I, Ura S, Moraes MO, Martinez AN, et al. Genetic diversity of Mycobacterium leprae isolates from Brazilian leprosy patients. Leprosy Review. [Article]. 2009 Sep;80(3):302-15. Lepr Rev.
<http://www.ncbi.nlm.nih.gov/pubmed/19393609 | _blank>> Buhrer-Sekula S, Illarramendi X, Teles RB, Penna MLF, Nery JAC, Sales AM, et al. The additional benefit of the ML Flow test to classify leprosy patients. Acta Tropica. [Article]. 2009 Ago;111(2):172-6.
Zelazny AM, Root JM, Shea YR, Colombo RE, Shamputa IC, Stock F, et al. Cohort Study of Molecular Identification and Typing of Mycobacterium abscessus, Mycobacterium massiliense, and Mycobacterium bolletii. Journal of Clinical Microbiology. [Article]. 2009 Jul;47(7):1985-95.
<http://www.ncbi.nlm.nih.gov/pubmed/19220476 | _blank>> de Lima CS, Marques MAM, Debrie AS, Almeida ECC, Silva CAM, Brennan PJ, et al. Heparin-binding hemagglutinin (HBHA) of Mycobacterium leprae is expressed during infection and enhances bacterial adherence to epithelial cells. Fems Microbiology Letters. [Article]. 2009 Mar;292(2):162-9.
<http://www.ncbi.nlm.nih.gov/pubmed/19706172 | _blank>> Williams DL, Slayden RA, Amin A, Martinez AN, Pittman TL, Mira A, et al. Implications of high level pseudogene transcription in Mycobacterium leprae. Bmc Genomics. [Article]. 2009 Aug;10-20.
<> Pinheiro RO, Nunes MP, Pinheiro CS, D'Avila H, Bozza PT, Takiya CM, Côrte-Real S, Freire-de-Lima CG, DosReis GA, Induction of autophagy correlates with increased parasite load of Leishmania amazonensis in BALB/c but not C57BL/6 macrophages, 2009, Microbes and Infection, volume 11, Issue 2, pages 181-90.
Martinez AN, Lahiri R, Pittman TL, Scollard D, Truman R, Moraes MO, et al. Molecular Determination of Mycobacterium leprae Viability by Use of Real-Time PCR. Journal of Clinical Microbiology. [Article]. 2009 Jul;47(7):2124-30.Journ of Clin Microb
<http://www.ncbi.nlm.nih.gov/pubmed/19821959 | _blank>> Altomare M, Nascimento AP, Romana-Souza B, Amadeu TP, Monte-Alto-Costa A. Ultrasound accelerates healing of normal wounds but not of ischemic ones. Wound Repair and Regeneration. [Article]. 2009 Nov-Dez;17(6):825-31.
<> Montoya D, Cruz D, Teles RMB, Lee DJ, Ochoa MT, Krutzik SR, et al. Divergence of Macrophage Phagocytic and Antimicrobial Programs in Leprosy. Cell Host & Microbe. [Article]. 2009 Oct;6(4):343-53.
Menezes VM, Sales AM, Illarramendi X, Miranda A, Morgado MG, Gutierrez-Galhardo MC, et al. Leprosy reaction as a manifestation of immune reconstitution inflammatory syndrome: a case series of a Brazilian cohort. Aids. [Article]. 2009 Mar;23(5):641-3. AIDS
Zelazny AM, Ding L, Elloumi HZ, Brinster LR, Benedetti F, Czapiga M, et al. Virulence and Cellular Interactions of Burkholderia multivorans in Chronic Granulomatous Disease. Infection and Immunity. [Article]. 2009 Out;77(10):4337-44. Infect. and Immun.
2008
Castro-pinto DB, Genestra M, Genestra M, Waghabi M, Gonçalves A, Gonçalves A, Leon LL, Mendonça-Lima L 2008. Cloning and expression of trypanothione reductase from a New World Leishmania species. Arch Microbiol 189: 375-384.
Araújo-Jorge TC, Waghabi MC, Soeiro MNC, Keramidas M, Bailly S, Feige J 2008. Pivotal role for TGF-beta in infectious heart disease: The case of Trypanosoma cruzi infection and consequent Chagasic myocardiopathy. Cytokine Growth Factor Rev 19: 405-413.
Pinto ME, Schrago CG, Miranda AB, Russo CAM 2008. A molecular study on the evolution of a subtype B variant frequently found in Brazil. Genet Mol Res 7: 1031-1044.
Otto TD, Vasconcellos EA, Gomes LH, Moreira AS, Degrave WM, Mendonça-Lima L, Alves-Ferreira M 2008. ChromaPipe: a pipeline for analysis, quality control and management for a DNA sequencing facility. Genet Mol Res 7: 861-871.
Guimarães AC, Otto TD, Alves-Ferreira M, Miranda AB, Degrave WM 2008. In silico reconstruction of the amino acid metabolic pathways of Trypanosoma cruzi. Genet Mol Res 7: 872-882.
Otto TD, Guimarães ACR, Degrave WM, Miranda AB 2008. AnEnPi: Identification and annotation of analogous enzymes. BMC Bioinformatics 9.
Otto TD, Gomes LH, Alves-Ferreira M, de Miranda AB, Degrave WM 2008. ReRep: computational detection of repetitive sequences in genome survey sequences (GSS). BMC Bioinformatics 9.
2007
Carvalho PC, Carvalho PC, Degrave WM, Lilla S, De Nucci G, Fonseca R, Spector N, Musacchio J, Domont GB 2007. Differential protein expression patterns obtained by mass spectrometry can aid in the diagnosis of Hodgkins disease. J Exp Ther Oncol 6: 137-145.
Gama BE, Pires, FESS, Lopes MKR, Cardoso MA, Britto CFPC, Torres KL, Mendonça-Lima L, Souza JM, Ribeiro CTD, Cruz MFF 2007. Real-time PCR versus conventional PCR for malaria parasite detection in low-grade parasitemia. Exp Parasitol 116: 427-432.
Oelemann MAC, Fontes ANB, Pereira MAS, Bravin Y, Silva G, Degrave WM, Carvalho ACC, Brito RC, Kritski A, Suffys PN 2007. Typing of Mycobacterium tuberculosis strains isolated in Community Health Centers of Rio de Janeiro City, Brazil. Mem Inst Oswaldo Cruz 102: 455-462.
Souza RA, Henriques C, Alves-Ferreira M, Mendonça-Lima L, Degrave WM 2007. Investigation of a protein expression profile by high-resolution bidimensional electrophoresis of Trypanosoma cruzi epimastigotes. Anal Biochem 365: 144-146.
Cuervo P, De Jesus JB, Junqueira M, Mendonça-Lima L, González LJ, Betancourt L, Grimaldi F. G, Domont GB, Fernandes O, Cupolillo E 2007. Proteome analysis of Leishmania (Viannia) braziliensis by two-dimensional gel electrophoresis and mass spectrometry. Mol Biochem Parasitol 154: 6-21.
Galvão TC, Mencía M, Lorenzo V 2007. Emergence of novel functions in transcriptional regulators by regression to stem protein types. Mol Microbiol 65: 907-919.
Teixeira RLF, Miranda AB, Pacheco AG, Lopes MQP, Fonseca-costa J, Fonseca-costa J, Melo HM, Kritski A, Mello FCQ, Suffys PN, Santos AR 2007. Genetic profile of the arylamine N-acetyltransferase 2 coding gene among individuals from two different regions of Brazil. Mutat Res 624: 31-40.
Waghabi M, Keramidas M, Calvet CM, Marcos Meuser Batista, Soeiro MNC, Mendonça-Lima L, Araújo-Jorge TC, Feige JJ, Bailly S 2007. SB-431542, a transforming growth factor beta inhibitor, impairs Trypanosoma cruzi infection in cardiomyocytes and parasite. Antimicrob Agents Chemother 51: 2905-2910.
2006
Catanho MP, Mascarenhas D, Degrave WM, Miranda AB 2006. BioParser: a tool for processing of sequence similarity analysis reports. Appl Bioinformatics 5: 49-53.
Catanho M, Mascarenhas D, Degrave W, Miranda AB 2006. GenoMycDB: a database for comparative analysis of mycobacterial genes and genomes. Genet Mol Res 5: 115-126.
Carvalho PC, Fischer JSG, Degrave WM, Carvalho MGC 2006. Marcadores séricos e espectrometria de massas no diagnóstico do câncer. J Bras Patol Med Lab 42: 431-436.
Carvalho PC, Freitas SS, Lima AB, Barros M, Bittencourt I, Degrave WM, Cordovil I, Fonseca R, Carvalho MGC, Moura-Neto RS, Cabello PH 2006. Personalized diagnosis by cached solutions with hypertension as a study model. Genet Mol Res 5: 856-867.
De Jesus JB, Ferreira MA, Cuervo P, Britto CF, Silva-Filho FCE, Meyer-Fernandes JR 2006. Iron modulates ecto-phosphohydrolase activities in pathogenic trichomonads. Parasitol Int 55: 285-290.
Cortes VF, Veiga-lopes FE, Barrabin H, Alves-Ferreira M, Fontes CFL 2006. The gamma subunit of Na+, K+-ATPase: role on ATPase activity and regulatory phosphorylation by PKA. Int J Biochem Cell B 38: 1901-1913.
Buschiazzo A, Goytia M, Schaeffer F, Degrave W, Shepard W, Grégoire C, Chamond N, Cosson A, Berneman A, Coatnoam N, Alzari PM, Minoprio P 2006. Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase. Proc Natl Acad Sci USA 103: 1705-1710.
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