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Área de PDI em Pesquisa, Desenvolvimento e Inovação em Doença de Chagas 2011

Adesse D, Goldenberg RC, Fortes FS et al. Gap junctions and chagas disease. Adv Parasitol. 2011. 76:63-81.

Adesse D, Azzam EM, Meirelles Mde N, Urbina JA, Garzoni LR. Amiodarone inhibits Trypanosoma cruzi infection and promotes cardiac cell recovery with gap junction and cytoskeleton reassembly in vitro. Antimicrob Agents Chemother. 2011 Jan;55(1):203-10. Epub 2010 Nov 15. http://aac.asm.org/cgi/content/abstract/55/1/203.

Alves FM, Olifiers N, Bianchi R de C et al. Modulating variables of Trypanosoma cruzi and Trypanosoma evansi transmission in free-ranging Coati (Nasua nasua) from the Brazilian Pantanal region. Vector Borne Zoonotic Dis. 2011 Jul;11(7):835-41. Epub 2010 Dec 13. Vector Borne Zoonotic Dis http://www.liebertonline.com/doi/abs/10.1089/vbz.2010.0096

Araújo CA, Waniek PJ, Xavier SC, Jansen AM. Genotype variation of Trypanosoma cruzi isolates from different Brazilian biomes. Exp Parasitol. 2011 Jan;127(1):308-12. Epub 2010 Jul 23.

Bambino-Medeiros R, Oliveira FO, Calvet CM, Vicente D, Toma L, Krieger MA, Meirelles MN, Pereira MC. Involvement of host cell heparan sulfate proteoglycan in Trypanosoma cruzi amastigote attachment and invasion. Parasitology. 2011 Apr;138(5):593-601. Epub 2011 Jan 270 http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8242208

Batista Dda G, Batista MM, de Oliveira GM, Britto CC, Rodrigues AC, Stephens CE, Boykin DW, Soeiro Mde N. 2011. Combined treatment of heterocyclic analogues and benznidazole upon Trypanosoma cruzi in vivo. PLoS One. 6(7):e22155.

Bourguignon SC, Cavalcanti DF, de Souza AM, Castro HC, Rodrigues CR, Albuquerque MG, Santos DO, da Silva GG, da Silva FC, Ferreira VF, de Pinho RT, Alves CR. Trypanosoma cruzi: insights into naphthoquinone effects on growth and proteinase activity. Exp Parasitol. 2011 Jan;127(1):160-6. Epub 2010 Jul 18.

Côrte-Real R, Gomes RN, Castro-Faria-Neto HC, Azambuja P, Garcia ES. The activity of platelet activating factor-acetyl hydrolase (PAF-AH) in the salivary glands of Rhodnius prolixus. J Insect Physiol. 2011 Jun;57(6):825-9.

Coura JR, Borges-Pereira J. Chronic phase of Chagas disease: why should it be treated? A comprehensive review. Mem. Inst. Oswaldo Cruz. 2011 Sep [cited  2011  Nov  18] ; 106(6): 641-645.

Coura JR, Junqueira A. Enfermedad de Chagas en la región amazónica: la última frontera, 2011, Biomédica , 31(sup.3):3-315

Da Silva CF, Junqueira A, Lima MM, Romanha AJ, Sales Junior PA, Stephens CE, Som P, Boykin DW, Soeiro Mde N. In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi. J Antimicrob Chemother. 2011 Jun;66(6):1295-7. J Antimicrob Chemother http://jac.oxfordjournals.org/content/66/6/1295.full.pdf+html

Daliry A, Pires MQ, Silva CF, Pacheco RS, Munde M, Stephens CE, Kumar A, Ismail MA, Liu Z, Farahat AA, Akay S, Som P, Hu Q, Boykin DW, Wilson WD, De Castro SL, Soeiro MN. 2011. The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA. Antimicrob Agents Chemother. 55(10):4765-73.

de Araújo FF, Vitelli-Avelar DM, Teixeira-Carvalho A, Antas PR, Assis Silva Gomes J, Sathler-Avelar R, Otávio Costa Rocha M, Elói-Santos SM, Pinho RT, Correa-Oliveira R, Martins-Filho OA. Regulatory T Cells Phenotype in Different Clinical Forms of Chagas' Disease. PLoS Negl Trop Dis. 2011;5(5):e992. Epub 2011 May 31.

de Castro SL, Batista DG, Batista MM, Batista W, Daliry A, de Souza EM, Menna-Barreto RF, Oliveira GM, Salomão K, Silva CF, Silva PB, Soeiro Mde N. 2011. Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones. Mol Biol Int. 2011:306928.

de Oliveira GM, Yoshida N, Higa EM, Shenkman S, Alves M, Staquicini D, Cascabulho C, Schor N. 2011. Induction of proinflammatory cytokines and nitric oxide by Trypanosoma cruzi in renal cells. Parasitol Res. 109(2):483-91.

De Souza EM, da Silva PB, Nefertiti AS, Ismail MA, Arafa RK, Tao B, Nixon-Smith CK, Boykin DW, Soeiro MN. Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi. Exp Parasitol. 2011 Feb;127(2):429-35.

Denise da G.J. Batista, Patrícia B. da Silva, Luciene Stivanin et al. Co(II), Mn(II) and Cu(II) complexes of fluoroquinolones: Synthesis, spectroscopical studies and biological evaluation against Trypanosoma cruzi. Polyhedron (June 2011), 30 (10), pg. 1718-1725. Polyhedron. http://www.sciencedirect.com/science/article/pii/S0277538711002221

Dias JC, Coura JR. 2011. Joaquim Romeu Cançado (1913-2011). Rev Soc Bras Med Trop. 44(4):532

Ennes-Vidal V, Menna-Barreto RF, Santos AL, Branquinha MH, d'Avila-Levy CM. MDL28170, a calpain inhibitor, affects Trypanosoma cruzi metacyclogenesis, ultrastructure and attachment to Rhodnius prolixus midgut. PLoS One. 2011 Apr 4;6(4):e18371.

Ferreira SB, Salomão K, de Carvalho da Silva F, Pinto AV, Kaiser CR, Pinto AC, Ferreira VF, de Castro SL. Synthesis and anti-Trypanosoma cruzi activity of β-lapachone analogues. Eur J Med Chem. 2011 Jul;46(7):3071-7. Epub 2011 Mar 15.

Ferreira LF, Jansen AM, Araújo A. Chagas disease in prehistory. An. Acad. Bras. Ciênc. 2011 Nov  18;  83 (3): 1041-1044.

Freitas SPC, Gonçalves TCM, Serrão JE, Costa J, Santos-Mallet JR. Ultrastructural Localization of Basic Proteins and Carbohydrates in Male Accessory Glands of Two Triatoma Species (Hemiptera, Reduviidae, Triatominae). J of Med Entomol, 48(3):496-503. 2011. http://www.bioone.org/doi/pdf/10.1603/ME10147.

Gomes SA, Vieira CS, Almeida DB, Santos-Mallet JR, Menna-Barreto RF, Cesar CL, Feder D. 2011. CdTe and CdSe quantum dots tcytotoxicity: a comparative study on microorganisms. Sensors (Basel). 11(12):11664-78.

Gonçalves RL, Barreto RF, Polycarpo CR, Gadelha FR, Castro SL, Oliveira MF. 2011. A comparative assessment of mitochondrial function in epimastigotes and bloodstream trypomastigotes of Trypanosoma cruzi. J Bioenerg Biomembr. 43(6):651-61.

Gonzalez MS, Silva LC, Albuquerque-Cunha JM, Nogueira NF, Mattos DP, Castro DP, Azambuja P, Garcia ES. 2011. Involvement of sulfated glycosaminoglycans on the development and attachment of Trypanosoma cruzi to the luminal midgut surface in the vector, Rhodnius prolixus. Parasitology. 9:1-8.

Henriques, C; Moreira, TLB; Maia-Brigagão, C; Henriques-Pons, A; Carvalho, TMC; Souza, W. Tetrazolium salt based methods for high-throughput evaluation of anti-parasite chemotherapy, Anal. Methods, 2011, 3, 2148. http://pubs.rsc.org/en/content/articlelanding/2011/ay/c1ay05219e

Herrera HM, Rocha FL, Lisboa CV, Rademaker V, Mourão GM, Jansen AM. Food web connections and the transmission cycles of Trypanosoma cruzi and Trypanosoma evansi (Kinetoplastida, Trypanosomatidae) in the Pantanal Region, Brazil. 2011. Trans R Soc Trop Med Hyg. Jul;105(7):380-7. Epub 2011 May 20. Trans R Soc Trop Med Hyg. http://www.sciencedirect.com/science/article/pii/S0035920311000836

Lannes-Vieira J, Pereira IR, Vinagre NF, Arnez LE. TNF-α and TNFR in Chagas disease: from protective immunity to pathogenesis of chronic cardiomyopathy. Adv Exp Med Biol. 2011; 691:221-30. Adv Exp Med Biol http://www.springerlink.com/content/r840h58262311587/

Magalhães BM, Coelho LI, Maciel MG, Ferreira JM, Umezawa ES, Coura JR, Guerra JA, Barbosa MG. 2011. Serological survey for Chagas disease in the rural areas of Manaus, Coari, and Tefé in the Western Brazilian Amazon. Rev Soc Bras Med Trop. 44(6):697-702.

Manque PA, Probst C, Pereira MC, Rampazzo RC, Ozaki LS, Pavoni DP, Silva Neto DT, Carvalho MR, Xu P, Serrano MG, Alves JM, Meirelles Mde N, Goldenberg S, Krieger MA, Buck GA. Trypanosoma cruzi Infection Induces a Global Host Cell Response in Cardiomyocytes. Infect Immun. 2011 May;79(5):1855-62. Epub 2011 Feb 22.

Meuser-Batista M, Corrêa JR, Carvalho VF et al. Mast cell function and death in Trypanosoma cruzi infection. Am J Pathol. 2011 Oct;179(4):1894-904. Epub 2011 Aug 3. Am J Pathol http://www.sciencedirect.com/science/article/pii/S0002944011006316

Morrot A, Terra-Granado E, Pérez AR, Silva-Barbosa SD, Milićević NM, et al. Chagasic Thymic Atrophy Does Not Affect Negative Selection but Results in the Export of Activated CD4+CD8+ T Cells in Severe Forms of Human Disease. 2011. PLoS Negl Trop Dis 5(8): e1268. PLoS Negl Trop Dis. http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001268

Nogueira RT, Nogueira AR, Pereira MC, Rodrigues MM, Galler R, Bonaldo MC. Biological and immunological characterization of recombinant Yellow Fever 17D viruses expressing a Trypanosoma cruzi Amastigote Surface Protein-2 CD8+ T cell epitope at two distinct regions of the genome. Virol J. 2011 Mar 18;8:127. http://www.virologyj.com/content/8/1/127/

Pérez AR, Silva-Barbosa SD, Berbert LR et al. Immunoneuroendocrine alterations in patients with progressive forms of chronic Chagas disease. J Neuroimmunol. 2011 Jun; 235(1-2):84-90. Epub 2011 Apr 14.

Prata A, Dias JC, Coura JR. 2011. The beginning of the disease. Rev Soc Bras Med Trop. 44 Suppl 2:6-11. Portuguese.

Ratcliffe NA, Mello CB, Garcia ES, Butt TM, Azambuja P. Insect natural products and processes: New treatments for human disease. Insect Biochem Mol Biol. 2011 Oct;41(10):747-69. Epub 2011 May 30. Insect Biochem Mol Biol http://www.sciencedirect.com/science/article/pii/S0965174811001093

Rosa Pérez A, Silva-Barbosa SD, Roggero E et al. Immunoendocrinology of the thymus in Chagas disease. 2011. Neuroimmunomodulation;18:328-338. Neuroimmunomodulation. http://content.karger.com/produktedb/produkte.asp?doi=329494.

Sarquis O, Oliveira LS, Rego R, Gonçalves JM, Lima MM, Maciel-de-Freitas R. Evaluation of RbCl and CrCl3 as markers of Triatoma brasiliensis (Hemiptera: Reduviidae) nymphs: persistence and influence of Rb and Cr on triatomine biology. Mem Inst Oswaldo Cruz. 2011 Jun;106(4):385-9.

Schijman AG, Bisio M, Orellana L, Sued M, Duffy T, Mejia Jaramillo AM, Cura C, Auter F, Veron V, Qvarnstrom Y, Deborggraeve S, Hijar G, Zulantay I, Lucero RH, Velazquez E, Tellez T, Sanchez Leon Z, Galvão L, Nolder D, Monje Rumi M, Levi JE, Ramirez JD, Zorrilla P, Flores M, Jercic MI, Crisante G, Añez N, De Castro AM, Gonzalez CI, Acosta Viana K, Yachelini P, Torrico F, Robello C, Diosque P, Triana Chavez O, Aznar C, Russomando G, Büscher P, Assal A, Guhl F, Sosa Estani S, DaSilva A, Britto C, Luquetti A, Ladzins J. International study to evaluate PCR methods for detection of Trypanosoma cruzi DNA in blood samples from Chagas disease patients. PLoS Negl Trop Dis. 2011 Jan 11;5(1):e 931

Soeiro M de N, de Castro SL. Screening of Potential anti-Trypanosoma cruzi Candidates: In Vitro and In Vivo Studies. Open Med Chem J. 2011 Mar; 5: 21–30.

Souza Rde C, Soares AC, Alves CL, Lorosa ES, Pereira MH, Diotaiuti L. Feeding behavior of Triatoma vitticeps (Reduviidae: Triatominae) in the state of Minas Gerais, Brazil. Mem Inst Oswaldo Cruz. 2011 Feb;106(1):16-22.

Vieira CS, Almeida DB, Thomaz AA, Menna-Barreto RF, Santos-Mallet JR, Cesar CL, Gomes SA, Feder D. Studying nanotoxic effects of CdTe quantum dots in Trypanosoma cruzi. Mem Inst Oswaldo Cruz. 2011 Mar;106(2):158-65.

Waniek PJ, Jansen AM, Araújo CA. 2011. Trypanosoma cruzi infection modulates the expression of Triatoma brasiliensis def1 in the midgut. Vector Borne Zoonotic Dis. 11(7):845-7.

Atualizado em 29/08/2012.

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